Cytochalasin B: effects on membrane ruffling, growth cone and microspike
activity, and microfilament structure not due to altered glucose transport.
Forest Rangers Chris DiCintio, Jason Seeley, David Nally, and Katherine Fox responded and provided the group with crampons and microspikes
. The fourth individual was stuck on a separate section of the falls, and a Ranger rapelled down to assist the hiker to a safer area.
Some cells also displayed actin-rich plasma membrane protrusions, such as filopodia and small punctate structures (microspikes
) (Figure 3(a)).
AMC even advised earlier guests to wear microspikes
just to cross the winter parking lot, which it called a sheet of ice.
These factors promote cell migration by activating the members of the Rho family of GTPases, Rac and Cdc-42 (26) and in the case of ECM adhesion and integrin mediated directed cell migration influenced by the mechanical rigidity of cell substrate (27), induces actin based lamellopodia, filopodia, and fascin containing microspikes
that drive cell extensions.
They had hiked up in zero-degree weather, with their headlamps lighting the way and microspikes
stretched over their boots giving them traction on the snow, and marveled at the stars in the night sky, the tiny headlights of the cars far below on Route 302, and the shadows of the hulking mountains that surround the notch.