emanate from [gamma]-tubulin at the poles (Fig.
75c) and the cytoplasm lobes around the plastid poles with substantial deposition of sporocyte wall material at the boundaries of the opposing microtubule
Then, the researchers put both greenand red-fluorescently labeled microtubules
into a channel.
are cylindrical hexagonal lattice polymers of the protein tubulin, comprising 15 percent of total brain protein.
However, this study found that microtubules
could additionally develop from the chromosomes themselves, or at arbitrary sites throughout the main body of the cell, if the centrosomes were missing.
When a spindle was cut into two fragments using glass microneedles, each fragment regained its original spindle shape and microtubule
density within five minutes of cutting (Figure 3).
Although the cells of plants and animals share many basic features, the encasement of plant cells within a rigid cell wall has led to unique microtubule
systems that have no counterpart in animal cells (Brown & Lemmon, 2001; Wasteneys, 2002).
extend down the length of axons--which transmit electrical signals in brain cells--serving as "superhighways of protein transfer," said Douglas Smith of the University of Pennsylvania in Philadelphia, who conducted the research with colleagues.
2004) have robust astral microtubule
arrays nucleated by centriole-containing centrosomes.
The role of microtubules
in cell biology, neurobiology, and oncology.
polymerization plays an essential role in cell division and entry into mitosis at the [G.
Tight regulation of microtubule
activity is critical to cell viability, and fine regulation of tau is likely to be equally important (2).