DNA sequence and phylogenetic analysis of zhikong scallop Chlamys farreri (Bivalvia: Pectinidae).
The researchers found that, compared with the control group, participants with type 1 diabetes had significantly lower mitochondrial
oxidative capacity, specifically at Complex II of the electron transport chain, with no between-group differences in mitochondrial
The company said that in an experimental study carried out in collaboration with researchers at Karolinska Instutet in Stockholm, Sweden, the project's model substance has shown favourable effects, which may counter disease progression in mitochondrial
In addition, other stimuli such as toxicants, protein degradation products and stress on other cofunctioning organelles also affect mitochondrial
function and may induce formation of mitochondrial
permeability transition pores that is an initial step to apoptosis .
A contributor to mitochondrial
dysfunction is the opening of a hole in the mitochondrial
inner membrane that decreases their ability to produce energy.
Experimental findings indicate that mitochondrial
processes often are deregulated in certain diseases, particularly in those affecting brain and muscle tissues, where energy requirements are ample, and therefore the mitochondrial
abnormalities are greatly highlighted.
focus on pluripotent stem cells and on the precise role played by mitochondrial
metabolites in maintaining pluripotency.
complex I activity detecting kit was bought from Nanjing Jiancheng Bioengineering Institute (Nanjing, China).
Mitochondria are ubiquitous powerhouses of eukaryotic cells and they provide organisms with adenosine triphosphate (ATP) by using a group of enzymes, gathered in the mitochondrial
electron transport chain (ETC), which transform transmembrane electron potential ([DELTA][[PSI].sub.m]) in biochemical energy.
Administration of Urolithin A leads to improved mitochondrial
function by stimulating mitophagy, a process by which aging and damaged mitochondria are cleared from the cell, leading to the growth of healthy mitochondria.
respiratory chain is one of the most important endogenous sources in the production of reactive oxygen species (ROS).