mtDNA

(redirected from Mitochondrial DNA)
Also found in: Dictionary, Thesaurus, Medical, Legal, Acronyms, Wikipedia.
Related to Mitochondrial DNA: Mitochondrial disease
References in periodicals archive ?
PROGNOSTIC IMPACT OF MITOCHONDRIAL DNA ALTERATIONS IN BRAIN TUMOR
Recently, mitochondrial DNA polymorphisms have been widely used to estimate the gene flow and phylogenetic relationships of maternal lineages in domestic animals (e.g., Nguluma et al., 2017; Jia et al., 2017; Deng et al., 2017; Almarzook et al., 2017) and wild animals (e.g., Elsner et al., 2017; Khaire et al., 2017).
Clinical heterogeneity associated with mitochondrial DNA A8344G point mutation (in Chinese).
(http://www.nature.com/news/regulators-weigh-benefits-of-three-parent-fertilization-1.13959) Opponents  of the procedure have not only raised ethical objections by questioning the psychological and social implications of children with three genetic parents, they have also said the technique should be avoided as the medical risks associated with changing mitochondrial DNA have yet to be fully understood.
Turnbull, "Mitochondrial DNA mutations in human disease," Nature Reviews.
But the study's finding does point to a larger relationship between mitochondrial DNA and aging and raises new questions about the long-term effects of creating three-parent babies.
"The study demonstrates that mitochondrial DNA levels are highly predictive of an embryo's implantation potential," Dr.
Mutations in mitochondrial DNA, which arise randomly within individual cells as we age, can limit cells' ability to create energy, produce signals and function properly.
Men with oligoasthenoteratozoospermiaharbor higher numbers of multiple mitochondrial DNA deletions in their spermatozoa but individual deletions are not indicative of overall aetiology.
Blood samples revealed participants had lower amounts of mitochondrial DNA with a higher amount of methylation than healthy people.
Mitochondrial DNA (mDNA) makes up about 0.1% of a cell's total DNA and does not affect individual characteristics such as appearance and personality.
The child would have "nuclear" DNA determining individual traits such as facial features and personality from its two parents, plus a tiny amount of mitochondrial DNA (mDNA) from an anonymous woman donor.

Full browser ?