mitogen


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Related to mitogen: Pokeweed mitogen

mitogen

[′mīd·ə‚jen]
(cell and molecular biology)
A compound that stimulates cells to undergo mitosis.
References in periodicals archive ?
Stimulation index (SI) of lymphocytes was calculated according to the formula: SI = number of cpm of lymphocytes incubated with mitogen: number of cpm of lymphocytes incubated without mitogen.
The proliferation response of splenic lymphocytes after mitogen stimulation
molleoides DME had significant stimulating effect on proliferation of normal murine splenocytes but inhibited proliferation of mitogen stimulated splenocytes and LB tumor cells.
mitogen activated protein kinase (MAPK) inhibitor that was exclusively in-licensed by Fulcrum Therapeutics following Fulcrum's discovery of the role of p38?/?
The integration of N-of-One clinical interpretation solutions into Sunquest Mitogen software expands the reach of precision medicine by making it easy for hospital pathology labs, commercial laboratories, and precision medicine programmes to obtain and deliver the highest-quality clinical interpretation of each patient's cancer, according to Chris Cournoyer, CEO of N-of-One.
The results showed that colloidal silver treatment did not affect significantly (p = 0.231) PBMC cell proliferation and cell count, and the treatments with mitogens Con A or PHA significantly (p = 0.05) increased the cell proliferation and cell count, compared with the untreated control; interestingly, the combined treatments with AgC/Con A or AgC/PHA significantly (p = 0.05) decreased the cell proliferation and cell count (Figures 2 and 3) of PBMC.
Mitogens (Sigma-Aldrich): concanavalin A (Con A) (25 [micro]g/ml), phytohemagglutinin (PHA) (25 [micro]g/ml), pokeweed mitogen (PWM) (2.5 [micro]g/ml), and antigen CD3 (3 [micro]g/ml) (Beckman Coulter) and BWD (0.12 and 75[micro]g/ml) were added in a volume of 25 [micro]l in different exposure intervals (4, 24, 48, and 72h).
Similarly, one can imagine autoactivating antibodies that preferentially activate downstream pathways, such as MAPK (mitogen activated protein kinase) growth pathways but not cAMP signaling.
Global Markets Direct's, 'Hepatocyte Growth Factor (Hepatopoietin-A or Lung Fibroblast Derived Mitogen) - Pipeline Review, H1 2016', provides in depth analysis on Hepatocyte Growth Factor (Hepatopoietin-A or Lung Fibroblast Derived Mitogen) targeted pipeline therapeutics.
Cheng, "TGF-[beta] regulates the blood-testis barrier dynamics via the p38 mitogen activated protein (MAP) kinase pathway: an in vivo study," Endocrinology, vol.
PPRV is lymphotropic as PPRV (Nigeria 75/1) is capable of infecting mitogen activated PBMCs and that presence of canine SLAM in Vero cell line greatly enhances infectivity of PPRV as compared to SLAM negative Vero.
Contributions cover formation of the vertebrate body axis, developmental control of biomechanics, mitogen activation of osteoblasts, pancreatic organogenesis, several items on stem cell coordination and renewal by local tissue signals, hormones, and microRNA, kin conflict in seed development, C.

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