mitogen

(redirected from mitogenic)
Also found in: Dictionary, Thesaurus, Medical.

mitogen

[′mīd·ə‚jen]
(cell and molecular biology)
A compound that stimulates cells to undergo mitosis.
References in periodicals archive ?
Perez et al., "The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines," Neuropeptides, vol.
Dunaif, "Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome," Diabetes, vol.
Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium.
The former refers to these factors mitogenic in both primary-cultured hepatocytes and in animal experiments, including hepatocyte growth factor (HGF), transforming growth factor- (TGF-) [alpha], epidermal growth factor (EGF), heparin-binding-EGF (HB-EGF), and their common receptor EGFR.
In the same way, it has been described that nuclear IR regulates the transcription of early growth response 1 (egr-1) and glucokinase (GK), which regulate mitogenic and metabolic responses, respectively [50].
Kenney, "[beta]-arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors," Cell Cycle, vol.
Although G1-arrested young cells can be reactivated to proliferating cells by treatment with serum or other mitogenic agents, senescent cells theoretically cannot overcome the G1 checkpoint.
Several lectins from distinct sources showed immunomodulatory effects, such as mitogenic activity (Figure 1(a)) and induction of T helper type 1 (Th1), type 2 (Th2), or type 17 (Th17) responses (Figure 1(b)).
This important research showed critical correlation between tumorigenic and mitogenic properties of melanoma and its ability to metastasize.
(2006) reported a reduced reaction to T cell-dependent and T cell- independent antigen in FAV-1-infected animals, along with a reduced mitogenic response of peripheral blood lymphocytes obtained from FAV-1 infected chicken after PHA-P stimulation.
Preud'homme, "Jacalin: a lectin mitogenic for human CD4 T lymphocytes," Clinical and Experimental Immunology, vol.
Quantification of growth factors in PRP and platelet-poor plasma (PPP) fractions revealed increased levels of mitogenic growth factors PDGF-AB, PDGF-BB, and FGF-2, the angiogenic agent VEGF and the chemokine RANTES in ucPRP compared to adult PRP (aPRP) and PPP.

Full browser ?