For those patients that were directed to the trial through Cancer Commons, one can go back to the scientists on whose research the molecular disease
model was based and ask them to revise the model based on the new molecular and clinical data from the subset of nonresponding patients.
Sickle cell anemia a molecular disease
. Science 1949;110:543-8.
Bryan Brewer, chief of the molecular disease
branch of the National Heart, Lung and Blood Institute at the National Institutes of Health (NIH), 60% of the estimated 13 million patients taking statins still have higher than recommended levels of LDL ("bad") cholesterol.
Bryan Brewer Jr., chief of the molecular disease
branch at the National Heart, Lung, and Blood Institute, Bethesda, Md.
This was a case of a molecular disease
, since an abnormal molecule, genetically produced, was the cause.