molecular entity


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molecular entity

[mə′lek·yə·lər ′en·təd·ē]
(chemistry)
A chemically or isotopically distinct atom, molecule, ion, complex, free radical, or similar unit that can be distinguished from other kinds of units.
References in periodicals archive ?
These projects include the clinical development of three products in Phase 3 and a new molecular entity in Phase 1, preparations for the upcoming release of two products for psoriasis in Europe, one is a biological product and to continue to support the new launchings during 2016 in the United States as well as growth in the aesthetic area.
ALKS 3831 is an investigational, novel, oral atypical antipsychotic drug candidate composed of samidorphan, a novel, new molecular entity co-formulated with the antipsychotic agent, olanzapine, in a single bilayer tablet.
It is a new molecular entity, resulting from the application of pegylation technology and it offers a new combination of demonstrated efficacy, a favourable safety profile consistent with the established interferon class and an every two-week dosing schedule.
They, along with efficacy, are critical properties in determining whether a new molecular entity will become a clinical candidate and subsequently, another drug on the market.
Considered a new molecular entity by the FDA, naproxcinod, which is taken orally, is enzymatically cleaved in vivo to release two active metabolites-naproxen and nitric oxide.
A phybrid is a peptide hybrid molecule that combines the pharmacological effects of two peptide hormones into a single molecular entity.
Tekturna, a new molecular entity (NME), is the first high blood pressure drug approved by FDA that inhibits renin, a kidney enzyme associated with the regulation of blood pressure.
At the same time, the new molecular entity is considered to have fewer deleterious peripheral side effects associated with estrogen-like activity.
It also reflects how Montaigne seems to touch and feel his environing world as a molecular entity, the knowledge of whose variety and life supersedes ideologies all the while one can grant them their passing privilege.
NU100 is a proprietary recombinant human interferon beta-1b (IFN beta-1b) being developed as a new molecular entity.
PLEGRIDY is a new molecular entity in which interferon beta-1a is pegylated to extend its half-life and prolong its exposure in the body.
Tyzeka is a new molecular entity, which is a term used by the FDA to describe a medication containing an active substance that has never before been approved for marketing in any form in the United States.

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