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Related to monkeypox: Monkeypox virus


rare disease caused by infection with the monkeypox virus, which is related to the viruses that cause smallpox and cowpox. The symptoms of monkeypox, which typically take 1 to 2 weeks to appear and last for 24 weeks, are similar to but milder than those of smallpox. Fever and chills, headache, muscle aches, and backache, and a feeling of exhaustion precede the development of swollen lympth nodes and a rash, which often first appears on the face before spreading elsewhere on the body; the rash lesions ultimately develop into pustules that open and then crust over. As many as 10% of cases result in death. There is no known treatment for monkeypox; the smallpox vaccine, antiviral drugs, and vaccinia immune globulin can be used to control an outbreak.

Human monkeypox infections occur when a person comes into contact with an infected animal or person or virus-contaminated materials such as bedding; the virus enters the body through a bite, scratch, or cut or abrasion in the skin or through the nose, mouth, or eyes. The virus is transmitted primarily by respiratory droplets, bodily fluids, or material from the lesions. Two distinct groups of monkeypox virus strains exist, Central African and West African. The latter generally results in milder cases with fewer deaths, and is not usually spread person to person.

Monkeypox was first identified in 1958 when outbreaks occurred in monkeys used for research; the disease also has been found in rodents. The first case in humans was recorded in 1970 in the Congo (Kinshasa). Monkeypox has since been reported in humans in other parts of central and W African. The only known outbreak outside Africa occurred in the United States in 2003; it was caused by a West African strain that came from small mammals imported from Ghana.

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(veterinary medicine)
An animal virus that causes a smallpox-like eruption but only rarely infects humans and has little potential for interhuman spread.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Species-specific identification of variola, monkeypox, cowpox, and vaccinia viruses by multiplex real-time PCR assay.
Health director-general Datuk Dr Noor Hisham Abdullah in a statement today, said it was false news and insisted there was no monkeypox infection detected in the country.
Symptoms in humans of monkeypox -- which is endemic in parts of Central and Western Africa -- include lesions, fever, muscle ache and chills.
Fortunately, cross-immunity exists between smallpox virus (variola), cowpox (vaccinia), and monkeypox. The latter is far milder and exhibits symptoms of headache, fever, chills, muscle aches, followed by a rash on the face followed by blisters, pustules, and scabs that eventually cover the entire body.
His partner became the third confirmed case of monkeypox in the UK when she broke out in spots last week.
Monkeypox does not spread easily between people and most who contract the infection recover within a few weeks, although severe illness can occur in some people.
A HEALTHCARE worker has become the third person in the UK to be struck down by monkeypox.
A HEALTHCARE worker in Blackpool has been diagnosed with Monkeypox - the third confirmed case of the virus in the UK.
THE third person to be diagnosed with monkeypox in the UK is currently in isolation at the Royal Victoria Infirmary in Newcastle.
A third person has been diagnosed with monkeypox in England, Public Health England have confirmed.
SMALLPOX vaccine has been given to health workers treating two victims of human monkeypox, it has been reported.