monokine


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monokine

[′män·ə‚kīn]
(biochemistry)
A cytokine released from macrophages.
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References in periodicals archive ?
Age-related changes in monokine production are not well delineated at this time; however, recent work comparing activated monocytes from older and young adults reveals diminished interleukin 1 (IL1) production, impairment of the oxidative burst, and a loss of tumoricidal capacity in monocytes from older adults.
Monokine induced by interferon gamma and IFN-gamma response to a fusion protein of Mycobacterium tuberculosis ESAT-6 and CFP-10 in Brazilian tuberculosis patients.
Itoh Y, Okanoue T, Sakamoto S, Nishioji K, Yasui K, Sakamoto M, Kashima K (1995) Monokine production by peripheral whole blood in chronic hepatitis C patients treated with interferon.
To clarify the immune responses mediated by ficolins in the placenta during preeclamptic pregnancy, we found that chemokines/cytokines involved in innate immunity, including monocyte chemoattractant proteins 1/2/3 (MCP1/2/3), monokine induced by gamma-interferon (MIG), macrophage inflammatory proteins 1[delta]/3[alpha] (MIP1[delta]/3[alpha]), tumor necrosis factor [alpha] (TNF[alpha]) and thymus expressed chemokine (TECK) were activated, whereas interferon/cytokines involved in adaptive immunity, including interferon [gamma] (IFN[gamma]), interleukin 13/4/5 (IL13/4/5), transforming growth factor [beta]1/[beta]3 (TGF[beta]1/[beta]3) and TNF[beta], were suppressed in preeclamptic placenta (n = 10 vs 10; Fig.
Serum concentrations of interleukin-8 (IL-8), monocyte chemoattractant protein (MCP) 1 (MCP-1) and monokine induced by IFN-[gamma] (MIG/CXCL9) are also elevated in both samples.
Lemaire 1(1991) Selective differences in macrophage populations and monokine production in resolving pulmonary granuloma and fibrosis.
3] Nonstandard abbreviations: VLBW, very low birth weight; DIC, disseminated intravascular coagulation; IL, interleukin; NEC, necrotizing enterocolitis; IP-10, interferon-[gamma]-inducible protein-10; MIG, monokine induced by interferon-7; MCP-1, monocyte chemoattractant protein-1; RANTES, regulated upon activation normal T cell expressed and secreted; TNF-[alpha], tumor necrosis factor-[alpha]; CRP, C-reactive protein; and ELR, glutamic acid-leucine-arginine.
17) studied 88 SARS patients with the same chemokine panel bead array assay and confirmed activation of chemokines, including IP-10, monokine induced by interferon-[gamma] (MIG), and monocyte chemoattractant protein-1 (MCP-1).