mononuclear

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Related to mononuclear phagocytes: thymus, reticuloendothelial cells

mononuclear

[¦män·ō′nü·klē·ər]
(cell and molecular biology)
Having only one nucleus.
References in periodicals archive ?
Low numbers of mononuclear phagocytes were also present and were occasionally noted to have a cytoplasmic vacuole containing small, thin, variably staining, linear to pleomorphic structures, consistent with bacteria (Fig 3).
Monocytes and macrophages, together with their precursors and dendritic cells, form the mononuclear phagocyte system (MPS) [31], although the identity of the dendritic cells remains disputed [32, 33].
Australia) presents 12 chapters exploring current knowledge of the biology and pathogenesis of lentiviral induced disease that occurs following infection of mononuclear phagocytes (i.
Treating tumors with nanoparticles has been challenging because immune cells called mononuclear phagocytes identify them and yank them from circulation, preventing the nanomaterials from reaching their target.
Monocytes and macrophages are leukocytes with a single-lobed nucleus that also act as phagocytes and which therefore also are called mononuclear phagocytes.
In order to understand the question of monocyte heterogeneity and recruitment, we need to first carefully define some terms including monocyte, heterogeneity, recruitment, mononuclear phagocytes, macrophages, inflammation.
A role for natural antibody in the pathogenesis of leprosy: antibody in nonimmune serum mediates C3 fixation to the Mycobacterium leprae surface and hence phagocytosis by human mononuclear phagocytes.
Contact with a persistent antigen that is poorly cleared by the immune system may lead to T lymphocytes and mononuclear phagocytes accumulating in the granulomas of sarcoidosis.
SUMMARY: The localization of peroxidase activity in different cell regions is used as a criterion for the classification of the stage of maturation of mammalian mononuclear phagocytes with a positive peroxidase reaction indicating the presence of monoblasts, promonocytes, monocytes and macrophages.