This includes the personal history of all individuals and all possible additional constraints or information (e.g.,
monozygous twins, genetic tests, and lethal alleles).
Monozygous twins discordant for clefting are interesting.
His center's study of more than 300 twins with epilepsy has now detected a concordance rate of 0.73 for generalized epilepsy among
monozygous twins.
In this case, the QF-PCR assay confirmed that the twins were
monozygous (MZ).
Concordance rates for T1D in
monozygous twins with long-term follow-up is >50%, compared to 6%-10% in dizygous twins, which is similar to what is found in nontwin siblings.
Glomerulocystic disease: a severe form in a
monozygous twin.
Possible explanation of high concordance for acute leukemia in
monozygous twins.
In 25% of
monozygous (identical) twin pairs in which one twin had SLE, the other twin developed SLE as well.
Contact allergy in
monozygous twins, Contact Dermatitis, 36, 52.
"It is an accepted medical doctrine that monochorionic twins are exclusively
monozygous," said Dr.
Initial zygosity studies performed on DNA from the twins' peripheral-blood lymphocytes indicated a 99.9% probability that they were
monozygous. Subsequent zygosity studies done on skin samples, however, indicated dizygosity; these findings were confirmed upon additional genetic analysis.