(discrete papular lichen myxedematosus)
SPAID, a spontaneously occurring auto-inflammatory disease, causes fever, swollen joints, cutaneous mucinosis
(a skin disorder), ear problems, and kidney failure.
3) Histopathologically, in addition to folliculotropism, features such as epidermotropism, syringotropism, follicular mucinosis
, and granulomatous inflammation can be seen as per the spectrum of atypical cutaneous lesions.
For example, if there is no lichenoid inflammation present histologically, the diagnosis is not lichen planus; absence of granulomata excludes sarcoidosis; lack of dermal mucin rules out a mucinosis
0-cm tumor was initially mistaken for reticular erythematous mucinosis
, a benign skin condition that occurs when fibroblasts produce abnormally large amounts of mucopolysaccharides.
Another change observed is dermal mucinosis
; cutaneous focal mucinosis
is characterized by asymptomatic flesh-colored papules or nodules occurring on extremities.
Rongioletti F, Rebora A: Updated classification of papular mucinosis
, lichen myxedematosus, and scleromyxedema.
Bullous systemic lupus erythematosus with cutaneous mucinosis
and leukocytoclastic vasculitis.
for hypothyroidism or acromegaly, calcinosis cutis for hyperadrenocorticism) are not present, histopathological findings of endocrinopathies are similar and may not reveal the origin of the problem.
Differential diagnosis includes other inflammatory disorders of the scalp like tinea capitis, or a variant of folliculotropic mycosis fungoides with follicular mucinosis
, and folliculitis decalvans, among other primary scarring alopecia.
Less frequent reactions at injection sites include vascular thrombosis, mucinosis
, dermal and SC sclerosis, necrosis, ulceration and rarely, lupus erythematosus-like lesions, sarcoidal granulomas, erythema nodosum, an acute septal panniculitis with neutrophils, lobular lymphocytic panniculitis and lipoatrophy.
Alopecia mucinosa; inflammatory plaques with alopecia characterized by root-sheath mucinosis