Although uncommon in children, a more generalized type of follicular mucinosis
can present very similar to lichen spinulosus.
Lymphocytic infiltration of the skin (Jessner-Kanof) but not reticular erythematous mucinosis
occasionally represents clinical manifestations of Borrelia-associated pseudolymphoma.
encompasses a heterogeneous group of skin diseases characterized by the deposition of mucin in the interval of the dermis (2).
No mucin deposition within the follicles (follicular mucinosis
) was seen (figure 3c).
Other differential diagnoses include self-healing juvenile cutaneous mucinosis
and acral persistent papular mucinosis
SPAID, a spontaneously occurring auto-inflammatory disease, causes fever, swollen joints, cutaneous mucinosis
(a skin disorder), ear problems, and kidney failure.
Interestingly, in a case of self-healing papular mucinosis
, which is a milder form of sclerodermoid lichen myxedematosus, CD34+ or FXIII-A-positive DCs have been described next to mast cells, suggesting that these cells together could contribute to the dermal mucin deposition of the lesions .
Other drugs that have been associated with PCA are hepatitis B vaccines causing Graham-Little-Piccardi-Lasseur syndrome , anticonvulsants and cyclosporine causing acne keloidalis nuchae (AKN) [34-36], and imatinib causing follicular mucinosis
(3) Histopathologically, in addition to folliculotropism, features such as epidermotropism, syringotropism, follicular mucinosis
, and granulomatous inflammation can be seen as per the spectrum of atypical cutaneous lesions.
For example, if there is no lichenoid inflammation present histologically, the diagnosis is not lichen planus; absence of granulomata excludes sarcoidosis; lack of dermal mucin rules out a mucinosis
. When certain inflammatory cells are absent, this should also be mentioned when relevant.
The painless, 3.0-cm tumor was initially mistaken for reticular erythematous mucinosis
, a benign skin condition that occurs when fibroblasts produce abnormally large amounts of mucopolysaccharides.
: Skin coloured or erythematous plaques favouring scalp, face, neck and shoulders.