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Related to multiple exostoses: Multiple congenital exostoses


A benign cartilage-capped protuberance from the surface of long bones but also seen on flat bones, caused by chronic irritation as from infection, trauma, or osteoarthritis.



a benign bony or bony-cartilaginous growth on the surface of a bone in the form of a linear or round mass. Exostoses develop mainly in males during childhood and adolescence, on the femur, tibia, humerus, and other bones. They cease to enlarge when bone growth ends. They usually do not cause complaints. However, fairly large exostoses compress muscles and nerve trunks, causing pain and hampering movement. The principal means of diagnosing exostoses is by X ray.

Exostoses are removed surgically if symptoms are pronounced or if the exostoses suddenly begin to grow rapidly in adults. Individuals suffering from exostoses are kept under clinical observation.

References in periodicals archive ?
Bechtold et al., "Unsuspected osteochondroma-like outgrowths in the cranial base of hereditary multiple exostoses patients and modeling and treatment with a BMP antagonist in mice," PLoS Genetics, vol.
The differential diagnosis of hereditary multiple exostoses includes the enchondromatosis, which are a heterogeneous group of syndromes that present with multiple enchondromas associated with pathological fractures, pseudarthrosis, limb shortening, malignant transformation risk, and scoliosis.
Raskind, "The natural history of hereditary multiple exostoses," The Journal of Bone and Joint Surgery.
Genetic heterogeneity in families with hereditary multiple exostoses. American Journal of medical genetics.1993, 53(1): 71-79.
For a review on hereditary multiple exostoses, please see the article by Wicklund et al.
l The support group can be contacted on 01438 861866 or by email at hmesg@ox 1.co.uk FACT FILE What is Hereditary Multiple Exostoses?Hereditary Multiple Exostoses (also known as HME, EXT, MHE, Diaphyseal Aclasis, Familial Bony Spurs) is a condition which can produce bony lumps close to the end of any bone, but particularly those of the limbs.
(6.) Bloch AM, Nevo Y, Ben-Sira L, Harel S, Shahar E: Winging of the scapula in a child with hereditary multiple exostoses. PediatrNeurol 2002; 26: 74-76.
The achievement of the 12-year-old from Gateshead is all the more commendable as he suffers from a very rare bone condition called hereditary multiple exostoses.
Christine Spencer, from Ouston, Chester-le-Street, is organising the event because her eight-year-old son Ryan has multiple exostoses, a condition where extra bone grows in and around joints, causing pain and discomfort.
She suffers from multiple exostoses, a rare inherited condition that causes bony lumps to grow at the end of some of her bones and press against her muscles.
Comparison of fluorescent single-strand conformation polymorphism analysis and denaturing high-performance liquid chromatography for detection of EXT1 and EXT2 mutations in hereditary multiple exostoses. EurJ Hum Genet 2000; 8:24-32.
Hosney, "The hip in hereditary multiple exostoses," The Journal of Bone & Joint Surgery--British Volume, vol.

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