mutation fixation

mutation fixation

[myü′tā·shən fik‚sā·shən]
(cell and molecular biology)
The condition of changing a premutational deoxyribonucleic acid lesion to mutation.
References in periodicals archive ?
This outcome is likely because all tissues are mitotically active during in utero development and therefore are susceptible to mutation fixation; in contrast, adult liver and brain have very low mitotic indices.