mutation fixation
mutation fixation
[myü′tā·shən fik‚sā·shən] (cell and molecular biology)
The condition of changing a premutational deoxyribonucleic acid lesion to mutation.
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This outcome is likely because all tissues are mitotically active during in utero development and therefore are susceptible to mutation fixation; in contrast, adult liver and brain have very low mitotic indices.
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