The endoneurium showed
myelinated and non-myelinated nerve fibres along with collagen bundles together with the endoneurial blood vessels.
1.5-h postketamine injection, a significant degeneration was observed in the spinal nerve roots,
myelinated nerve fibers, lamellae, axoplasm, Schwann cell cytoplasm, and nucleus, in some regions, condensation was observed in the axoplasm.
The first
myelinated axons appear to be those into and/or out of long-projecting pyramidal neurons.
Figure 6 shows the mean
myelinated axon number which was 7116 for the control group, while for the rats at 7, 14, 21, and 28 days after operation it was 5535, 6281, 6624, and 6620, respectively, with significant differences between the control group and each of the experimental groups.
Porges says, "If we feel safe, we have access to the neural regulation of the facial muscles, we have access to a
myelinated vagal circuit that is capable of downregulating more traditional fight/flight and stress responses, and we have an opportunity to play." Play, such as a game of tag, lets mammals engage in social interaction that mimics the fight/flight response while indicating nonaggression with facial and voice cues.
(20) Therefore, the localization of NEDD8 in the
myelinated fibers was examined by double immunostaining using specific antibodies against NEDD8 and MAG.
Nerve fiber structure in D-gal-treated mice
Myelinated fibers from the control mice appeared compact and homogeneous with integral sheaths; whereas the fibers from the D-gal-treated mice showed dilatation with irregular contours in which some sheaths displayed obvious splitting and vacancy in some places (Fig.
Ultrastructural and morphometric studies of the peripheral nerves reveal loss of unmyelinated and small
myelinated fibers and no innervation to the sweat glands.
The middle of one straight
myelinated fiber with length of 63 mm was placed below the center of the proximal electrode and was oriented parallel to the z-axis.
Large A-delta
myelinated fibres and small C unmyelinated fibres are mainly responsible for carrying nociceptive sensations.
While intra1 antibody(red) exclusively labels MBP-positive fibers (green) and highlights myelin structures, c-ter antibody does not immunoreact with
myelinated fibers, being present on cells likely resembling microglia (insets), as also confirmed by colocalization with microglial marker CD11b (data not shown).
When the axon is not
myelinated it 'shorts out' and can cause unpredictable connections.
