myeloid


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.

myeloid

[′mī·ə‚lȯid]
(anatomy)
Of or pertaining to bone marrow.
Of or pertaining to the spinal cord.
References in periodicals archive ?
Some of this research was conducted in collaboration with the MDS Foundation an international non-profit advocacy organization whose mission is to support and educate patients and healthcare providers with innovative research into the fields of MDS, AML and related myeloid neoplasms.
Although trisomy 8 is one the most common chromosomal abnormalities observed in hematological malignancies (4), polysomy 8 is a rare, non-random numerical abnormality associated with myeloid malignancies such as acute myelod leukemia (AML), myelodysplastic syndromes (MDS) and rarely myeloproliferative disorders (MPDs) (4, 5).
As TET2 is a key regulator in hematopoietic stem cell renewal and differentiation, their mutations result in increased stem cell renewal and myeloid hyperplasia with impaired differentiation.
Genetic testing incorporating both cytogenetic karyotyping and molecular analysis has an important role in defining and classifying AML patients.10 Specific cytogenetic and molecular features defining specific disease entities permit classification of AML patients.11 These genetic molecular markers help predict the likelihood of attaining a complete remission and subsequent disease-free survival in patients of acute myeloid leukaemia.4 Information regarding the genetic landscape of AML and its impact on prognosis is important in guiding treatment decisions.1
Cancer recruit harmful myeloid cells, while suppressing helpful ones
This category includes AML with germline CEBPA mutation and myeloid neoplasms with germline DDX41 mutation.
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder predominantly of adult life, having a male preponderance.1 These patients have variable presentations.2 Some are completely asymptomatic, their disease being diagnosed incidentally on routine blood CP while others may have symptoms due to anemia or splenomegaly.3 CML is usually diagnosed on peripheral blood film but the detection of the BCR-ABL fusion transcript by molecular techniques is necessary for establishing a definitive diagnosis.4
The company has introduced XOSPATA (generic name: gilteritinib) for prescription in the US for the treatment of adult patients who have relapsed or refractory (resistant to treatment) Acute Myeloid Leukemia (AML) with a FLT3 mutation as detected by an US FDA-approved test.
CEBPA Mutation: CEBPA, a transcription factor in hematopoietic stem cells, is responsible for the differentiation to the myeloid progenitors and functions as a promoter for myeloid and monocytic differentiation (16).
Material and Methods: Seventy eight patients of Chronic Myeloid Leukemia (CML) in chronic phase (CP) were included in the study.
Sadly, however, he died just three months after diagnosis with acute myeloid leukaemia.
Is it BPDCN or mature pDCs proliferation coexisted with myeloid tumor?