myelophthisic anemia

(redirected from myelophthisic)
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myelophthisic anemia

[¦mī·ə·lō′this·ik ə′nē·mē·ə]
(medicine)
An anemia associated with space-occupying disorders of the bone marrow. Also known as leukoerythroblastic anemia; leukoerythroblastosis; metastatic anemia; myelopathic anemia; myelosclerotic anemia; osteosclerotic anemia.
References in periodicals archive ?
Generalized marrow expansion is a response to a systemic process, such as anemias, tumors, and other myelophthisic states.
Bone marrow examination can also detect myelophthisic disorders, such as acute leukemia, lymphoma, or metastatic malignancy, which could explain a patient's thrombocytopenia.
Immunological and Hematological Disorders: Patients with AIDS, hemoglobinopathies, immunologically mediated hemolytic processes, myelophthisic conditions, sickle cell anemia, systemic lupus erythematosus, beta thalassemia, or chronic hemolytic anemia (from conditions such as multiple cardiac valve replacement) often respond poorly to conventional Epoetin alfa dosing regimens.
Giant basal cell carcinoma with metastases and myelophthisic anemia.
Myelophthisic anemia secondary to rectal carcinoma is unprecedented in our experience and consistent with previous observations that bony metastases are rare.[1,2] The finding of a myelophthisic process in a patient undergoing radical resection for localized rectal carcinoma may, therefore, direct consideration toward a primary hematologic malignant neoplasm or a second malignant neoplasm metastatic to the bone marrow.