myelophthisis


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myelophthisis

[¦mī·ə·lō′this·əs]
(medicine)
Loss of bone marrow.
Atrophy of the spinal cord.
References in periodicals archive ?
Postow, "Response after treatment with pembrolizumab in a patient with myelophthisis due to melanoma: the role of checkpoint inhibition in the bone," Journal for ImmunoTherapy of Cancer, vol.
HIV infection may lead to anaemia by changes in cytokine production with subsequent effects on haematopoises, decreased erythropoietin production, due to treatment with HAART drugs, nutritional deficiency, opportunistic infection, malignancy and myelophthisis of marrow caused by lymphoma.
(27) The anemia and thrombocytopenia can be caused by myelophthisis; however, in people with CLL, immune-mediated cytopenias are also common.
FIGHERA & BARROS (2004) observed no granulomatous inflammatory infiltrates in the bone marrow of the six vetch-intoxicated cattle from which this tissue was examined, but those animals did not have either a hemorrhagic disease as the cow in this case, which had changes in the bone marrow typical of myelophthisis secondary to the granulomatous myelitis.
High number of circulating CD34+ cells in patients with myelophthisis. Haematologica 2005; 90: 976-7.
The low hematopoietic cell count was attributed to myelophthisis. These findings were consistent with a well-differentiated lymphoid malignancy in the bone marrow and supported a diagnosis of chronic lymphocytic leukemia (CLL).