Preliminary immunohistochemical new findings in the
myenteric plexus of patients with intestinal neuronal dysplasia type B.
Poles et al., "Gut region-specific diabetic damage to the capillary endothelium adjacent to the
myenteric plexus," Microcirculation, vol.
Overall number of ganglion cells in the
myenteric plexus between longitudinal and circular muscle layer of adult colon was 16.31 [+ or -] 3.81 ganglion cells/[mm.sup.up.2] and 8.86 [+ or -] 1.79 ganglion cells/[mm.sup.up.2] in its rectum.
(13,14) In the literature, a study reported that the rate of achalasia was elevated among patients with BN compared to the general population, (7) and there are some case reports about BN patients developing achalasia because of
myenteric plexus damage.
Summing up, it could be said that the quercetin supplementation in diabetic animals promotes a set of metabolic changes that lead to an increase of weight loss and a slight reduction in blood glucose, whereas the NADHd neurons in the
myenteric plexus of the ileum maintains the nucleus and cytoplasm volume and reduces neuronal loss.
Moreover, the highest level of HO1 and HO2 expression in the tissue homogenates of the control duodenum (including the smooth muscle layers of the gut wall and the
myenteric plexus between them) also highlights an intensified protective environment in this particular gut segment and emphasizes the importance of the neuronal microenvironment [10, 12].
This phenomenon could well be related to the degeneration of autonomic neurons in the
myenteric plexus and brainstem [45].
The longitudinal muscle strip with the
myenteric plexus attached was separated from the underlying circular muscle according to the method of Paton and Vizi [29].
In the
myenteric plexus, progressive activation of p38 MAPK was observed in all groups (Figure 1E).
Control group (Figures 5(a) and 6(a)) shows the dense c-Kit-positive cellular network (ICC-DMP), located between the longitudinal and circular muscularis and at the innermost part of the circular muscularis, and intermingled with the
myenteric plexus. Between the circular muscle fibers, there was abundance of VAChT/nNOS-positive nerve fibers and c-Kit-positive cellular network run parallel with the muscle fibers.
MMIHS patients typically have abnormalities in the muscle layer,
myenteric plexus, or the interstitial cells of Cajal (ICCs) [24, 25].
Effect of protein and vitamin B deficiency on the morphoquantitative aspects of the
myenteric plexus of the descending colon of adults rats.