We investigated the effect on [V.sub.pp] for UEGM-D and UEGM-ME2 when gradually increasing the distance between the ablation catheter and the myocardium
(see Figure 8).
Pathological Changes of the Myocardium
after BMSCs Intervention.
The fibrosis was calculated as the percentage of blue-stained connective tissue areas per total myocardium
After administered to rats at a dosage of 200 mg/kg for 28 days before MI model, GBE significantly decreased the heart enzymes CK, AST and LDH in plasma and increased them in myocardium
compared to the model group (P<0.01, Tables 1 and 2).
Stollberger and Finsterer refined the definition as >3 trabeculations protruding from the LV wall apical to the papillary muscles, perfused intertrabecular spaces, and atwolayered myocardium
with the noncompacted layer usually thicker than the compacted myocardium
in end-systole .
In addition, AlloCSC-01 has displayed a strong tropism for the heart enabling a high retention of cells in the myocardium
after intracoronary administration.
In addition, resting echo-cardiograph measures were taken to establish morphology characteristics of the myocardium
. These included left ventricular mass (LVM, gm), left ventricular internal diameter end-diastolic (LVIDd, cm), left ventricular internal diameter endsystolic (LVIDs, cm), septal wall thickness (SWT, cm), and posterior wall thickness (PWT, cm).
In case of combined development of ischemic and diabetic damage of myocardium
we obtained essentially less manifested change of ES contraction dynamics.
The histological pattern observed ranges from normal myocardium
to acquired fibrotic changes superimposed on the background of normal myocardium
Non-compaction of the myocardium
was first described by Bellet et al., from an autopsy carried out on a newborn in whom aortic atresia and coronary-ventricular fistula were also observed.
The outer one was in direct contact with myocardium
and was composed of irregularly arranged connective tissue that merge with collagen and elastic fibres surrounding the adjacent cardiac muscle along with Purkinje fibres, blood vessels, and lymphatics.
The counter-argument to this is that the cardiac blood supply is unique, with the majority of the myocardium
being perfused during diastole.