myoepithelial cells


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Related to myoepithelial cells: myofibroblast

myoepithelial cells

[‚mī·ō‚ep·ə′thē·lē·əl ‚sel]
(histology)
Contractile epithelial cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion.
References in periodicals archive ?
Ohlin, "Secretory activity and the myoepithelial cells of salivary glands after duct ligation in cats," Archives of Oral Biology, vol.
Pleomorphic adenomas of the nasal cavity differ from those found elsewhere in that they have more myoepithelial cells and little or no stromal component.
Whereas ductal and milk-producing cells secrete the water and nutriments essential for the survival of young mammalian offspring, the myoepithelial cells, through their contraction, guide the circulation of the milk throughout the ductal tree toward the nipple.
Another interesting observation is that some myoepithelial cells of the normal mesothelium show condensation of their myofilaments into compact spindle-like structures (SLSs).
Absence of myoepithelial cell layer by immunohistochemical study is significant for pathologic diagnosis.
The resultant ETV6-NTRK3 fusion product is a constitutively active chimeric tyrosine kinase and has transformation capacity in the mammary epithelial and myoepithelial cells. (3) One report (6) showed that MASC did not have the mutations associated with 50 common cancer-related genes or methylation of Ras association domain family 1 isoform A (RASSF1A) and retinoic acid receptor [beta]2 (RARB2), which had been observed in other malignant salivary gland tumors.
The admixed myoepithelial cells show spindle to plasmacytoid morphology.
The tumor was composed of neoplastic myoepithelial cells arranged in a fascicular nested pattern separated by collagen stroma (Figure 1).
Smooth muscle myosin heavy chain (SMMHC) stained focal myoepithelial cells around the larger lobules (Figure 6).
It is believed that the tumour is ER negative not a result of poor differentiation, but possibly due to preserved polarity and differentiation of the component epithelial and myoepithelial cells (1).
Myoepithelioma is an uncommon tumor of the myoepithelial cells that is considered to represent a distinct category of tumor by the World Health Organization.