myofilament


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Related to myofilament: myofibril, thin filaments

myofilament

[¦mī·ō′fil·ə·mənt]
(cell and molecular biology)
The structural unit of muscle proteins in a muscle cell.
References in periodicals archive ?
Changes in myofilament proteins, but not [Ca.sup.2+] regulation, are associated with a high-fat diet-induced improvement in contractile function in heart failure.
Medusozoans include scyphozoans, hydrozoans, and cubozoans, all of which contain muscle cells generally described as elongated cells with contractile myofilaments of either smooth or striated organization (Calgren, 1949).
However, in the DM and DM + SGES groups (Figures 6(b) and 6(c)), SMC was arranged in disorder with irregular nucleus, the chromatin was massive with dark staining, many large cytoplasm lysis vacuoles were distributed intracellularly, dense bodies and myofilaments were decreased, and there was swelling in the mitochondria as well as vacuolar degeneration and dissolution.
A [Ca.sup.2+] transient serves as an input to the cell myofilament model representing the generation of active tension within each myocyte in which an ODE set and multiple algebraic equations describe [Ca.sup.2+] binding to troponin C, cooperatively between regulatory proteins, and cross-bridge cycling.
In model group of AMI rats, part of myocardial myofilament ruptured and exposed.
Postmortem changes in the myofilament lattice spacing generate the driving force for drip loss, but the actual direction of the muscle fibers during storage has a great influence on drip loss [3,13].
Both mechanisms raise the load of the sarcoplasmic reticulum (SR) resulting in an increase of systolic [Ca.sup.2+]-transients as well as an increase in myofilament sensitivity [18].
vulgaris, has been shown to increase myocardial contractility by increasing myofilament [Ca.sup.2+]-sensitivity via a protein kinase C[epsilon]-dependent signaling pathway (Zhang et al., 2011).
Lipopolysaccharide depresses cardiac contractility and B-adrenergic contractile response by decreasing myofilament response to calcium in cardiac myocytes.
The mechanism of rhabdomyolysis in palytoxin poisoning is via palytoxin's sodium channel opening effects which prolong depolarization causing muscle spasms with myofilament damage and rhabdomyolysis.
Solaro, "Expression of tropomyosin-[kappa] induces dilated cardiomyopathy and depresses cardiac myofilament tension by mechanisms involving cross-bridge dependent activation and altered tropomyosin phosphorylation," Journal of Muscle Research and Cell Motility, vol.
Troponin I is a myocardial specific myofilament component, a monomer with molecular mass of 24 KDa.