myoinositol


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myoinositol

[¦mī·ō·i′näs·ə‚tȯl]
(biochemistry)
The commonest isomer of inositol. Also known as mesionositol.
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The aim of this study was to investigate and compare both the mRNA and protein expression of myoinositol transporters in the peripheral nervous system during experimental diabetes.
Increased myoinositol (mI), increased mI/ Cr ratio is noted in advanced NCL.
As the most important stereoisomer of inositol, myoinositol has pivotal roles in cell metabolism and is the precursor of all inositol compounds, including phosphoinositides (PI), inositol phosphates (InsPs), inositol sphingolipids, and glycosylphosphatidylinositols.
In 1H-spectroscopy, elevated peaks of lipid, lactate, choline, and myoinositol and reduced NAA signal are typical findings in primary brain tumors [45,46].
Phytate ([C.sub.6][H.sub.18][O.sub.24][P.sub.6]), also known as phytic acid (myoinositol 1,2,3,4,5,6-hexakisphosphate; PA; [IP.sub.6]), has a molecular weight of 660 g mol-1 (Figure 1) and is considered the main source of stored phosphorus in seeds, grains, and vegetables.
Baillargeon, "Hyperinsulinemia alters myoinositol to d-chiroinositol ratio in the follicular fluid of patients with PCOS," Reproductive Sciences, vol.
In another 1H-NMR human study, several metabolites (maltose, glucose, biotine, methylamine, inosine, methylguanidine, creatine, myoinositol, and quinolinic acid) were found significantly changed in septic neonates at the onset of the disease [28].
Activation of the polyol pathway enhances the synthesis of the sorbitol that has toxic, osmotic activity and reduces the concentration of myoinositol. At the same time, due to the oxidation of nicotinamide adenine dinucleotide phosphate (NAD(P)H) and the reduction of nicotinamide adenine dinucleotide (NAD+), redox imbalance is created.
Phytase is an enzyme, chemically known as myoinositol (1, 2, 3, 4, 5, 6) -hexaphosphate phosphohydrolase, and mainly catalyses the hydrolysis of phytate rendering P available for absorption.
Myoinositol, a sugar alcohol which can be produced by the body and is found in many foods, has been used at higher doses as a supplement in children and adolescents with bipolar disorder, as an adjunct to treatment with some promising results.
Instead, studies revealed a high degree of metabolic consistency focused on the catabolism of alpha amino acids, gamma aminobutyric acid, and myoinositol. The ability to catabolize sugars and short-chain fatty acids was inconsistent within and between ants.
Dietary inositol hexakisphosphate, but not myoinositol, clearly improves hypercholesterolemia in rats fed casein-type amino acid mixtures and 1,1,1-trichloro-2,2-b/s (p-chlorophenyl) ethane.