myotonic dystrophy


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myotonic dystrophy

[¦mī·ə¦tän·ik ′dis·trə·fē]
(medicine)
A hereditary disease, transmitted as an autosomal dominant, characterized by lack of normal relaxation of muscles after contraction, slowly progressive muscular weakness and atrophy, especially of the face and neck, cataract formation, early baldness, gonadal atrophy, abnormal glucose tolerance curve, and, frequently, mental deficiency.
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Participants with mild-to-moderate adult-onset myotonic dystrophy (by physician report) attending an academic neuromuscular clinic were invited to participate.
He predicts that researchers will identify the gene underlying myotonic dystrophy "in the very, very near future .
Anesthetic management of a patient with myotonic dystrophy for a Nissen fundoplication and gastrostomy.
When injected into the muscle cells of mice with myotonic dystrophy, the molecule found its way to the cell nucleus, broke up the deposits of toxic RNA, freed the captive muscleblind proteins, and ultimately improved the function of the muscle cells.
5] Nonstandard abbreviations: CK, creatine kinase; CK-M and -B, CK-muscle and -brain, respectively; AMI, acute myocardial infarction; Ab, antibody; UTR, untranslated region; CK-mit, mitochondrial CK; and DM, myotonic dystrophy.
Two genetic abnormalities have been identified that are responsible for myotonic dystrophy types 1 and 2 (DM-1, DM-2).
This study is important as it is the first study in which we will be observing the effects of our drug in patients with myotonic dystrophy, and it is the first study in which we are targeting a toxic RNA," said C.
Her death certificate said she died of a cardiac arrest, pneumonia, marasmus - progressive emaciation caused by lack of food - and congenital myotonic dystrophy.
7, 2014 /PRNewswire-USNewswire/ -- Eric Wang, Sharif Bordbar, Albert Almada, and Chris Anselmo, colleagues from MIT, Harvard, and Boston College, together with the Myotonic Dystrophy Foundation (MDF) and Parent Project Muscular Dystrophy (PPMD)-will host the 2[sup.
Lindsay Gentry was afflicted with a condition called congenital myotonic dystrophy, and was 4 feet 8 inches tall and weighed 50 pounds when she died in February 1996 at Kaiser Foundation Hospital in Fontana.
Afflicted with a congenital condition called myotonic dystrophy, Lindsay Gentry was 4 feet 8 inches tall and weighed 50 pounds when she died Feb.