Caption: Figure 2: Photomicrographs of hematoxylin and eosin sections: (A) microcystic/reticular foci with a myxoid
appearance adjacent to denser spindle cell areas (100x magnification); (B) microcystic areas with vacuolated cells; and (C) bland spindle cells with palisading configurations (B&C: 400x magnification).
In PN, there is Pacinian corpuscle-like differentiation in the myxoid
Mandahl et al., "Rearrangement of the transcription factor gene CHOP in myxoid
liposarcomas with t(12;16)(q13;p11)," Genes Chromosomes and Cancer, vol.
Focal pseudoglandular formation was evident, set in a myxoid
and sclerotic stroma.
Microscopic Picture Showing Densely Collagenised Stroma (Right side) and Dilated Vessels with Myxoid
MIFS is defined as a locally aggressive fibroblastic neoplasm that occurs primarily in distal extremities and is characterized by epithelioid fibroblasts with macronucleoli interspersed with a prominent mixed inflammatory infiltrate and variable myxoid
Well-differentiated and myxoid
tumors rarely develop distant metastases, and five-year survival rates for these tumors are 83-100%.
Diagnostic utility of molecular investigation in extraskeletal myxoid
Microscopic examination showed histological features of a mesenchymal neoplasm composed of loosely arranged plump to spindle-shaped myofibroblastic cells in an edematous myxoid
background with proliferating blood vessels and an infiltrate of plasma cells, lymphocytes, and eosinophils [Figure 2].
Histologically, these tumors are produced from the cells in a random sequence in a myxoid
matrix without an infiltrative growth pattern, mitotic activity, cytological atypia or necrosis (3,4).
Three histologic types were observed among the 21 cases: 14 storiform-pleomorphic (or pleomorphic), 3 giant cells, and 4 myxoid
. In 11 cases, tumors were located in the body and/or tail of the pancreas and left pancreatectomy and splenectomy were performed.
liposarcoma is the second most common subtype (MLs).