nalorphine


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Related to nalorphine: naloxone

nalorphine

nalorphine (nălˈərfēn), derivative of morphine that acts to reverse the effects of morphine and other narcotics. It counteracts narcotic-induced nervous system and respiratory system depression but is not effective against depression induced by other sedatives such as barbiturates. Nalorphine and other narcotic antagonists are useful in reversing the effects of narcotic overdoses. Because nalorphine causes withdrawal symptoms in addicts, it is administered to apparent ex-addicts to determine if they have returned to drug use. Nalorphine is marketed under the trade name Nalline.
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References in periodicals archive ?
Cardiovascular effects of morphine, pethidine, diamorphine and nalorphine on the cat and rabbit.
Gluten therefore, by its "molecular mimicry" of endorphins (and enkephalins) reacts with the brain's endorphin receptors in the same deleterious way as cyclazocine or nalorphine. Casein proteins in dairy products are also thought to have similar amino acid sequences to enkephalin, thus also capable of interacting with brain receptors.
It is equal in potency as analgesic to morphine, and one-fourth as potent as nalorphine as an antagonist.