naproxen


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Related to naproxen: cyclobenzaprine

naproxen

and

naproxen sodium,

potent nonsteroidal anti-inflammatory drugs (NSAID) used to alleviate the minor pain of arthritis, menstruation, headaches, and the like, and to reduce fever. Along with ibuprofenibuprofen
, nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, fever, and inflammation. Along with naproxen and ketoprofen, ibuprofen belongs to the propionic acid class of NSAIDs. It was first made available in 1967.
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 and ketoprofenketoprofen
, nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and fever-reducing effects, used to relieve the symptoms of headaches, arthritis, and painful menstruation.
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, they belong to the propionic acid class of NSAIDs. They have been available as prescription drugs for arthritis from 1976. Naproxen sodium was approved at a low dosage as an over-the-counter painkiller in the United States in 1994; it was first marketed under the tradename Aleve. Side effects may include gastrointestinal distress and dizziness, and renal impairment has been reported in some instances with long-term use. The drugs should not be used by those who are allergic to aspirinaspirin,
acetyl derivative of salicylic acid (see salicylate) that is used to lower fever, relieve pain, reduce inflammation, and thin the blood. Common conditions treated with aspirin include headache, muscle and joint pain, and the inflammation caused by rheumatic fever and
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References in periodicals archive ?
Applying the APS to a trial sample of 200 people (100 assigned to naproxen and 100 to placebo) the INTREPAD results showed real changes over the two-year trial period.
After giving their informed consent and completing a baseline questionnaire, patients were randomized to receive either naproxen as a single 750-mg dose, then as 250 mg three times a day for a maximum of seven days, which is the licensed dose for gout in the United Kingdom, or 500 mcg of colchicine three times a day for four days.
Diazepam is no better than placebo when added to naproxen for acute low back pain.
The main secondary endpoint was met when no subjects treated with ATB-346 exhibited ulcers of more than 5 mm diameter versus 24% of subjects treated with naproxen, with an average of 2.5 ulcers per subject.
or the nonselective NSAIDs ibuprofen at 600-800 mg three times a day or naproxen at 375-500 mg twice daily.
The highest risk was found to be in the first month of taking the pills and to those on a high daily dose - such as more than 1,200mg of ibuprofen, 750mg of naproxen and 25mg rofecoxib.
The study claims using NSAIDs at a high dose for eight to 30 days was "particularly harmful" when people took more than 1200mg a day of ibuprofen, 750mg a day of naproxen and more than 25mg a day of rofecoxib.
According to the company, VIMOVO (naproxen/esomeprazole magnesium) is a fixed-dose combination of delayed-release enteric-coated naproxen, a non-steroidal anti-inflammatory drug (NSAID), and immediate-release esomeprazole magnesium, a stomach acid-reducing proton pump inhibitor (PPI), approved for the relief of signs and symptoms of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis and to decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers.
Researchers from Cleveland Clinic and Brigham and Women's Hospital, Boston, embarked on a 10-year trial (Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen or Naproxen, or PRECISION), involving 24,081 patients in 13 countries to investigate the relative cardiovascular safety of celecoxib compared to ibuprofen and naproxen.