Vasculitis

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vasculitis

[‚vas·kyə′līd·əs]
(medicine)
Inflammation of a blood vessel or a lymph vessel. Also known as angiitis.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Vasculitis

 

inflammation of the walls of the small blood vessels. Vasculitis is usually caused by influenza, typhus, streptococcal infections (erysipelas, angina), or physical factors (frostbite, burns). Vasculitis may also arise as a secondary manifestation of collagen or allergic diseases, such as rheumatism, lupus erythematosus, rheumatoid arthritis, and serum and drug diseases. Sometimes vasculitis may be caused by a combination of some of these factors. The most usual, and often the only, external symptom of vasculitis is affection of the skin (hemorrhages, rashes, necrotic nidi, and so forth). As vasculitis progresses, thrombi may form in the vessels (thrombovasculitis), necrosis of the walls of the vessels may occur, and aneurysms may form. In the final stage of vasculitis complete occlusion of the vessels by a thrombus may occur, which leads to the disrupting of nutrition to the corresponding tissues and organs, bursting of aneurysms, and hemorrhaging into the surrounding tissues. Vasculitis is classified according to site as cutaneous and visceral; the latter predominantly affects the vessels of serous and mucous membranes of internal organs, such as the liver and kidneys. Treatment consists of the removal of the main disease causing the vasculitis.

REFERENCE

Davydovskii, I. V. Patoligicheskaia anatomiia i patogenez boleznei cheloveka, 3rd ed., vols. 1-2. Moscow, 1956-58.

IU. I. ZAK

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Although rare, necrotizing vasculitis should be considered in the differential diagnosis of acute abdominal pain or fever of unknown origin because, like in our case, an early diagnosis could contribute to not only treatment but also the prevention of severe abdominal manifestations, such as perforation or intra-abdominal bleeding.
We identified a novel circovirus, DogCV, in the liver of a dog that had necrotizing vasculitis and granulomatous lymphadenitis.
The cANCA pattern is usually associated with Wegener's granulomatosis (WG) [13, 14] which is a form of necrotizing vasculitis that occurs mainly in Caucasian adults and involves the small- and medium-size blood vessels with formation of granulomata and commonly affects the respiratory, ocular, and renal systems [15].
It showed necrotizing vasculitis with evidence of granuloma formation in 4 cases while the rest of cases showed chronic non specific inflammation.
In the skin biopsy, in one patient (case no.5) done about a year prior to present condition was suggestive of necrotizing vasculitis (Fig.
Nonspecific findings include urticarial vasculitis of the small vessels, necrotizing vasculitis of small or medium vessels, diffuse alopecia, and pyoderma gangrenosum.
The patient's diagnoses included microscopic polyangiitis, systemic necrotizing vasculitis, leukocytuclastic vasculitis, and glomerulonephritis.
Dwight Robinson of Harvard Medical School showed that in mice fed with fish oil the incidence of glomerulitis, one kind of kidney disease, was reduced, while necrotizing vasculitis, another kind of kidney disease, seemed to be aggravated by the supplement.
Surgical biopsy of the lung nodule showed necrotizing vasculitis that affected pulmonary arteries with granulomatous changes.