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Inflammation of a blood vessel or a lymph vessel. Also known as angiitis.



inflammation of the walls of the small blood vessels. Vasculitis is usually caused by influenza, typhus, streptococcal infections (erysipelas, angina), or physical factors (frostbite, burns). Vasculitis may also arise as a secondary manifestation of collagen or allergic diseases, such as rheumatism, lupus erythematosus, rheumatoid arthritis, and serum and drug diseases. Sometimes vasculitis may be caused by a combination of some of these factors. The most usual, and often the only, external symptom of vasculitis is affection of the skin (hemorrhages, rashes, necrotic nidi, and so forth). As vasculitis progresses, thrombi may form in the vessels (thrombovasculitis), necrosis of the walls of the vessels may occur, and aneurysms may form. In the final stage of vasculitis complete occlusion of the vessels by a thrombus may occur, which leads to the disrupting of nutrition to the corresponding tissues and organs, bursting of aneurysms, and hemorrhaging into the surrounding tissues. Vasculitis is classified according to site as cutaneous and visceral; the latter predominantly affects the vessels of serous and mucous membranes of internal organs, such as the liver and kidneys. Treatment consists of the removal of the main disease causing the vasculitis.


Davydovskii, I. V. Patoligicheskaia anatomiia i patogenez boleznei cheloveka, 3rd ed., vols. 1-2. Moscow, 1956-58.


References in periodicals archive ?
We identified a novel circovirus, DogCV, in the liver of a dog that had necrotizing vasculitis and granulomatous lymphadenitis.
Necrotizing vasculitis as a complication of propylthiouracil.
It showed necrotizing vasculitis with evidence of granuloma formation in 4(20%) cases while the rest of cases showed chronic non specific inflammation.
5) had necrotizing vasculitis of the skin (a year ago), known to be associated with B19 virus (Fig.
During a medical screening program for former Department of Energy (DOE) workers by the Johns Hopkins University Former Los Alamos National Laboratory (LANL) Workers Program (Espanola, NM) a 63-year-old white male expressed concern that his diagnoses of microscopic polyangiitis, systemic necrotizing vasculitis, leukocytoclastic vasculitis, pulmonary interstitial fibrosis, and glomerulonephritis were related to silica exposure.
Dwight Robinson of Harvard Medical School showed that in mice fed with fish oil the incidence of glomerulitis, one kind of kidney disease, was reduced, while necrotizing vasculitis, another kind of kidney disease, seemed to be aggravated by the supplement.
As a group, the AAVs were defined broadly as "a necrotizing vasculitis, with few or no immune deposits, predominantly affecting small vessels, and associated with MPO-ANCA or PR3-ANCA.
Various vasculitic & vasculopathic processes have been associated with IDUs including urticarial vasculitis, Churg Strauss vasculitis, Raynaud phenomenon, Henoch Schonlein purpura, necrotizing vasculitis, Buerger's disease & pseudo-vasculitis.
Necrotizing vasculitis persists as an extremely serious condition where complicated diagnostic and treatment decisions may need to be made on an urgent and chronic basis.
Histopathologic findings included a marked lympho-histiocytic fibrinoid necrotizing vasculitis affecting small blood vessels and arterioles in the kidney and liver (Figure) and associated with lymphocytic interstitial nephritis and mild multifocal granulomatous hepatitis.