negative staining

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negative staining

[′neg·əd·iv ′stān·iŋ]

(biology)

A method in microscopy for demonstrating the form of cells, bacteria, and other small objects by staining the ground rather than the objects.

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Caption: Figure 2: (a) Photomicrograph immunohistochemical ([IHC] x400) showing malignant cells with negative staining for CD-45.

Metachronous nasopharyngeal carcinoma masquerading as a base of skull metastasis in a case of primary extraskeletal vulvar Ewing's sarcoma

Immunohistochemical stain on cell block showing negative staining for Thyroglobulin (Thyroglobulin stain X 200).

Fine needle aspiration cytology of pulmonary papillary adeno-carcinoma mimicking papillary thyroid carcinoma

Immunohistochemical stains for basal cells, such as HMWCK or more recently p63 are currently used in the diagnosis of focal prostate cancer but there are limitations in their use as negative staining for basal cell markers is by itself not diagnostic of carcinoma and also due to technical reasons these stains may be falsely positive thus it is necessary to interpret negative staining in an atypical focus in light of positive staining in adjacent benign glands which is used as an internal positive control.

IMMUNOHISTOCHEMICAL EXPRESSION OF ALPHA METHYLACYL-COA RACEMASE (AMACR) IN CARCINOMA PROSTATE IN PAKISTANI POPULATION

No membrane debris, observed by electron microscopy using negative staining confirmed the purity of OMVs from both strains.

Isolation and characterization of OMPs and OMVs of Brucella abortus S19 and Brucella abortus S19[DELTA]per

[37.] Rodriguez C, Hardy E (2015) Lipopolysaccharide aggregates in native agarose gels detected by reversible negative staining with imidazole and zinc salts.

Lipopolysaccharide (LPS) and protein-LPS complexes: detection and characterization by gel electrophoresis, mass spectrometry and bioassays

Histological examination of a renal leiomyoma reveals fusiform to spindle shaped cells with positive immunohistochemical staining for smooth muscle markers (desmin, caldesmon, and SMA) and negative staining for HMB-45 and cathepsin K.

Leiomyoma in a Renal Allograft

Negative staining for lymphatic marker, (D) D2-40, excluding an adenomatoid tumour of the testis.

Capillary hemangioma of the testis: a rare benign tumour

The negative staining technique of Heine is a simple, inexpensive, and efficient way of screening for Cryptosporidium parvum and Cystoisospora belli [4].

Modified negative staining of Heine for Fast and inexpensive screening of Cryptosporidium, Cyclospora, and Cystoisospora spp

In addition, when a positive staining for CEA and a negative staining for CAL were considered as an indication of malignancy, the sensitivity of cytological and immunocytochemical results was shown to be 97%, with 100% specificity, a positive predictive value of 100%, a negative predictive value of 95%, and an overall accuracy of 98%.

Evaluation of the sensitivity and specificity of immunohistochemical markers in the differential diagnosis of effusion cytology

We observed a similar percentage (46.4%) of cases with negative staining in adjacent non-neoplastic mucosa.

Immunohistochemical expression and significance of NM23 suppressor protein in primary gastric adenocarcinoma

Among these cases with a negative staining pattern, a positive serologically elevated serum tTG was seen in the four cases where it was measured.

Utility of tissue transglutaminase immunohistochemistry in pediatric duodenal biopsies: patterns of expression and role in celiac disease--a clinicopathologic review

Although pituitary adenomas can have somewhat similar morphologic features, the presence of strong and diffuse TTF-1 nuclear expression with negative staining for pituitary hormones excludes the diagnosis of a pituitary adenoma.

Carcinoid tumor of the lung metastatic to a previously identified pituitary adenoma