A methodologically weak negative study
may harm the science more as compared to the methodologically weak positive study.
In general, this is a reasonably important negative study
. It stands in contrast to some previous evidence and current popular theories, and it points out the lack of significant influence on platelets counts of an effective iron supplementation (IV route).
"It will be viewed as a largely negative study
and people who are enthusiasts for omega fatty acids will continue to be enthusiasts and people who are sceptics will continue to be sceptics," said Scott Wright of the Mayo Clinic in the United States, who was not involved in the research.
Wedbush Securities analyst Liana Moussatos reaffirmed a "Neutral" rating on the stock with a $15 price target, but said the negative study
results could push shares below $5.
This climate of mistrust has been fueled by reports of negative study
results being withheld by industry as well as falsified data being presented by academic investigators, thus questioning the validity of support for drugs and devices.
"I don't prescribe it for women over 65 because of the negative study
data, but I do have patients who started earlier and have been on it for 25 to 30 years.
Even if his statement was supported by a negative study
, it relates to emissions and not concentrations.
On the downside pharmaceutical stock GlaxoSmithKline remained under pressure falling 27p to 1307p as investors continued to fret over the recent negative study
relating to diabetic drug Avandia.
One study that did not show diuretic activity used the root and another negative study
administered the preparation intraperitoneally.
Practicing clinicians should use power to determine the impact of a negative study
. For example, the propranolol study (1) was designed with a power of only 23%, meaning that there was only a 23% chance of detecting a difference.
The results of a negative study
may provide useful information concerning other areas within the business unit.
It is important to note that immunoreactivity for Epstein-Barr virus is helpful in establishing a diagnosis of PTLD, but a negative study
does not exclude the presence of PTLD.