Zhao and Nemere
 pointed out that with the growth of broilers, 1,25[D.sub.3]-MARRS (membrane activated rapid response to steroids) mRNA expression and PKC (protein kinase C) activity were decreased.
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In this disease patients will develop symptoms related to growth retardation (unproportional growth stature) and rachitic skeletal deformities mainly in upper and lower limbs [Farach-Carson and Nemere