hyperplasia

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hyperplasia

(hī'pərplā`zhə): see hypertrophyhypertrophy
, enlargement of a tissue or organ of the body resulting from an increase in the size of its cells. Such growth accompanies an increase in the functioning of the tissue. In normal physiology the growth in size of muscles (e.g.
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The Columbia Electronic Encyclopedia™ Copyright © 2013, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.

Hyperplasia

 

an increase in the number of structural elements of tissues or organs. In man and animals, hyperplasia is based on the intensified reproduction of cells and the formation of new structures. Hyperplasia is observed in various types of pathological growth of tissues (chronic productive inflammation and tumor), in regeneration, and in hypertrophy. Hyperplasia often carries with it compensating characters. In plants, it may be a local growth of tissues resulting from mitotic or amitotic cell division. It occurs with infection by destructive or pathogenic organisms, during trauma, and under the influence of growth stimulants, pesticides, and other preparations. The result of hyperplasia is the formation of galls, calluses, and warts.

The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.

hyperplasia

[‚hī·pər′plā·zhə]
(medicine)
Increase in cell number causing an increase in the size of a tissue or organ.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Preventive effects of MMP-3 in venous neointima via gene transfer and deteriorative role of MMP-3 found in carotid neointimal hyperplasia using genetic knockout seem paradoxical.
RESORB study found that the degree of neointimal hyperplasia was similar to that of BMS.
EPCs derived from human early fetal aortas could be successfully transplanted into injured vessels and may inhibit neointimal hyperplasia after vascular injury.
Morphometric examination of the anastomosed arteries from the PBS group showed different degrees of neointimal hyperplasia. The intimal cross-sectional area (112.509[+ or -]61.179 [micro][m.sup.2]*1000 PBS anastomozed group vs.
Furthermore, together with the impact of the arterial wall injury, a multifactorial process is initiated, leading to neointimal hyperplasia and restenosis.
Long-term outcomes of neointimal hyperplasia without neoatherosclerosis after drug-eluting stent implantation.
"With 400 patients and a technology such as IVUS [intravascular ultrasound], we could have quantified, to the millimeter, differences in neointimal hyperplasia and only then embarked on a huge trial."
[sup][5],[6],[7] This leads to the suggestion that sarpogrelate is a candidate for inhibiting 5-HT-induced neointimal hyperplasia (restenosis) after angioplasty.
Objective: The purpose of this study was to compare the effects of ticlopidine and clopidogrel on the development of neointimal hyperplasia after experimental arterial injury.
Bypass grafts are prone to neointimal hyperplasia: Vein grafts have this process mostly at anastomosis sites, diffuse disease occurs with synthetic materials.
Angiography at 6-month follow-up showed the scaffold remained patent without significant neointimal hyperplasia. In-scaffold MLD and percent of diameter stenosis was 2.73 mm and 8.8% respectively, therefore the in-scaffold late luminal loss was calculated as 0.22 mm [Figure 1]e.