neomorph


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Related to neomorph: hypomorphic allele, Neomorphic mutation

neomorph

[′nē·ə‚mȯrf]
(genetics)
A mutant allele that produces an effect different from that produced by the normal allele.
References in periodicals archive ?
Under the terms of this agreement, NeoGenesis will use its drug discovery technologies, including its proprietary ALIS (Automated Ligand Identification System) platform, NeoMorph compound libraries and lead optimization technologies to discover drug candidates against selected targets.
Its core technology includes the Automated Ligand Identification System (ALIS), a scalable, generic, affinity-based system for rapidly screening disease-associated targets; and a NeoMorph compound library, consisting of more than 10 million different molecules.
Coupled with the company's NeoMorph compound library, consisting of more than 10 million diverse medicinally relevant small molecules, ALIS identifies small molecule ligands exhibiting high affinity and high selectivity against many protein classes.
The discovery of lead molecules for this particular target, related to human cardiovascular disease, had proven elusive prior to the application of NeoGenesis' ALIS (Automated Ligand Identification System) screening technology, and its NeoMorph library of millions of drug-like compounds.