neomycin


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neomycin

(nē'ōmī`sĭn), broad spectrum antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 effective against both gram positive and gram negative bacteria (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
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). It interferes with protein synthesis in sensitive bacterial cells such as species of Proteus and Staphylococcus. Neomycin is mainly used topically in the treatment of skin and mucous membrane infections, wounds, and burns. Although it is also used systemically, it is highly toxic. Neomycin was first isolated in 1949 by the American microbiologist Selman Waksman from a strain of the bacterial species Streptomyces fradiae.

neomycin

[¦nē·ə¦mīs·ən]
(microbiology)
The collective name for several colorless antibiotics produced by a strain of Streptomyces fradiae; the commercial fraction (C23H46N6O13) has a broad spectrum of activity.
References in periodicals archive ?
Conclusion: Topical Ciprofloxacin is a better drug for the treatment of CSOM as compared to topical Neomycin.
As neomycin exposure concentrations increased, damaged and missing kinocilia were often observed (Figs.
As per present study the clinical cases of colibacillosis in calves were effectively treated by ciprofloxacin followed by gentamicin, neomycin and co-trimoxazole which was comparable with in-vitro study and should be recommended for the field use.
For example, Timor and co-worker have synthesized a set of modified neomycin B analogues by adding additional sugar at the C5''-OH of ring III and prepared a series of pseudo-pentasaccharides 1a- d (Fig.
As with all aminoglycosides, neomycin is limited in its clinical applications due to its serious adverse effects (Adams & Holland, 2011).
Susceptibilities to bacitracin and neomycin were tested by the Kirby-Bauer disk diffusion method (Becton Dickinson, Franklin Lakes, NJ, USA).
Can cause anaphylactic reaction to previous mumps vaccine, eggs, or neomycin.
In these experiments, neomycin sulfate was used in the RIA but not in the Ang I-generation mixture used for LC-MS/MS.
A synergistic effect of CPZ on gentamicin or neomycin was not observed, which suggested the occurrence of other resistance mechanisms or of a CPZ insensitive efflux pump that can be blocked by EEHM in the case of gentamicin (Table).
Results: The most common allergens identified were: carba mix, nickel sulphate, thiuram mix, paratertiary butylphenol formaldehyde resin, paraphenylenediamine, and neomycin sulphate.
azedarach) was used as a negative control, while neomycin skin ointment (0.