neomycin

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neomycin

(nē'ōmī`sĭn), broad spectrum antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
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 effective against both gram positive and gram negative bacteria (see Gram's stainGram's stain,
laboratory staining technique that distinguishes between two groups of bacteria by the identification of differences in the structure of their cell walls. The Gram stain, named after its developer, Danish bacteriologist Christian Gram, has become an important tool
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). It interferes with protein synthesis in sensitive bacterial cells such as species of Proteus and Staphylococcus. Neomycin is mainly used topically in the treatment of skin and mucous membrane infections, wounds, and burns. Although it is also used systemically, it is highly toxic. Neomycin was first isolated in 1949 by the American microbiologist Selman Waksman from a strain of the bacterial species Streptomyces fradiae.
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neomycin

[¦nē·ə¦mīs·ən]
(microbiology)
The collective name for several colorless antibiotics produced by a strain of Streptomyces fradiae; the commercial fraction (C23H46N6O13) has a broad spectrum of activity.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Material Active principle Presentation Rifocort[R] Sodium rifamycin SV21-prednisolone Ointment Acetate Nebacetin[R] Neomycin sulfate Ointment Bacitracin 2%-Chlorhexidine 2%-Chlorhexidine digluconate Gel digluconate Maxitrol[R] Neomycin sulfate Ointment Polymyxin b sulfate Dexamethasone Material Properties Rifocort[R] Antimicrobial Antiinflammatory Nebacetin[R] Antimicrobial 2%-Chlorhexidine Antimicrobial digluconate Maxitrol[R] Antimicrobial Antiinflammatory Table 2.
(41) In a retrospective review of patch testing reactions from 587 adult patients, neomycin sulfate and thimerosal elicited a hypersensitivity reaction in 53% and 18% of the patients, respectively.
tetracycline hydrochloride 89 10 [micro]g tetracycline hydrochloride + 10 [micro]g ND-497 71 10 [micro]g ND-497 66 20 [micro]g ND-497 64 20 [micro]g erythromycin 91 10 [micro]g erythromycin + 10 [micro]g ND-497 80 20 [micro]g streptomycin sulfate 70 10 [micro]g streptomycin sulfate + 10 [micro]g ND-497 62 20 [micro]g polymyxin B sulfate 72 10 [micro]g polymyxin B sulfate + 10 [micro]g ND-497 62 20 [micro]g neomycin sulfate 87 10 [micro]g neomycin sulfate + 10 [micro]g ND-497 62
These drugs include neomycin sulfate, paromomycin, natamycin, ketoconazole, ciclopirox olamine, [23] pentamidine isethionate, propamidine isethionate, stilbamidine isethionate, [24] amphotericin B, sulfadiazine, sulfisoxazole, sulfamethoxazole, polymyxin B and E, [25] and clotrimazole.
Nystatin (Tystatin) Oral Suspension; Dexamethasone Sodium Phosphate + Neomycin Sulfate (Archidex) eyeear drops; Lansoprazole 30 mg delayedrelease capsule; Ketoconazole (Ninazol) 200 mg tablet; Paracetamol (SaRa) 500 mg tablet;
Ang1 (Fluka Biochemicals); [[Val].sup.5]Ang1, phenylmethylsulfonyl fluoride (PMSF), and soybean trypsin inhibitor (Sigma Chemical Co.); and maleic acid and neomycin sulfate (ICN Chemicals) were purchased from their respective suppliers.