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Neurologic sequelae of neonatal hypoglycemia in Kayseri, Turkey J Child Neurol 2008; 23(12): 1406-12.
Significantly less neonatal hypoglycemia was found in metformin plus insulin group, P [less than or equal to] 0.01, and mean blood glucose levels at birth were also better in metformin plus insulin group (Table 3).
[Ak.sub.1]2-1 phenotype in diabetic pregnant women may herald severe maternal hyperglycemia and neonatal hypoglycemia. Diabetic mothers with this phenotype carried a risk of dissociation between birth weight and placental weight that could increase the susceptibility to perinatal morbidity and mortality and cardiovascular diseases in adulthood.
Neonatal hypoglycemia is caused by congenital hyperinsulinism that can extend hypoglycemic episodes beyond the neonatal period and is also strongly associated with brain damage and deficit in neurological development [73].
One infant in the intervention group had MRI abnormality attributable to neonatal hypoglycemia but this infant had neither seizures nor recurrence of hypoglycemia after enrolment.
Postprandial testing was associated with lower rates of large-for-gestational-age offspring, fewer cesarean sections, and less neonatal hypoglycemia. It appears that the fetal pancreas is most sensitive to the height of blood glucose excursions, which typically occur after meals.
This condition can result in transient neonatal hypoglycemia, which is common in infants of mothers with diabetes.
Neonatal hypoglycemia. Neonatal Network, 16(2), 15-21.
Neonatal hypoglycemia can arise in a baby neurologically intact at birth and free of any inherited disorder.
Gestational weight gain above the amount recommended by IOM guidelines was significantly associated with adverse outcomes in neonates, including macrosomia (adjusted odds ratio, 2.66), shoulder dystocia (aOR, 1.74), and neonatal hypoglycemia (aOR, 1.60).

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