Lupus(redirected from neonatal lupus)
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See R. G. Lahita and R. H. Phillips, Lupus: Everything You Need to Know (1998).
Lupus(loo -pŭs) (Wolf) A constellation in the southern hemisphere near Centaurus, lying partly in the Milky Way, with several stars of 2nd magnitude. There are many naked-eye double stars and several globular and open star clusters. Abbrev.: Lup; genitive form: Lupi; approx. position: RA 15.3h, dec –45°; area: 334 sq deg.
(or lupus vulgaris), the most severe and frequent form of skin tuberculosis. The causative agent of tuberculosis (mycobacterium tuberculosis) may invade the skin from without after an injury, but much more frequently it comes from internal organs and lymph nodes affected by tuberculosis. The course and symptoms of the disease vary greatly because they are determined by the virulence of the causative agent, point of entry, location of the disease, and general condition of the patient. The first symptom of the disease is a hyperemic spot that lightens when pressed; a tubercle soon develops. Under the pressure of a glass slide, it turns pale, and the lesion shows through as a pale yellow spot (the “apple jelly” phenomenon). Because the tissue in the affected area loses its elasticity, the tubercle is easily injured and bleeds readily. The tubercles gradually coalesce, forming large plaques. While the center of the plaque heals, forming a white scar as thin as cigarette paper (tubercles may again appear there), increasing numbers of fresh tubercles appear at the periphery. The epidermis covering the plaques thins and desquamates. Sometimes the tubercles become ulcerous; ulcers with a tubercular base may also develop. Lupus generally affects the face (nose, cheeks, ears), the extremities, and, less commonly, the trunk. The mucous membranes of the nose and mouth are often affected. Lupus occurs more frequently in children. The chronic course of the disease may result in disfigurement (eversion of the eyelids, narrowing of the mouth and nares, etc.) and occasionally in malignant degeneration. Thanks to modern methods of treatment and close follow-up of the patients, lupus has become less common and its prognosis is better. The disease is treated with a complex of antituberculous drugs, vitamin D2, multiple vitamins, tonics, physical therapy, sunbaths, and climatotherapy.
REFERENCENeradov, L. A. “Tuberkulez kozhi.” In Mnogotomnoe rukovodstvo po dermato-venerologii, vol. 2. Edited by S. T. Pavlov. Leningrad, 1961.
M. A. ROZENTUL
(the Wolf), a constellation in the southern sky. Its brightest star is 2.3 in visual stellar magnitude. The most favorable conditions for viewing Lupus are in April and May. It is visible in the southern regions of the USSR.