nephrosis


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Related to nephrosis: hydronephrosis

nephrosis

(nəfrō`səs), kidney disease characterized by lesions of the epithelial lining of the renal tubules, resulting in marked disturbance in the filtration function and the consequent appearance of large amounts of protein (albumin) in the urine (see urinary systemurinary system,
group of organs of the body concerned with excretion of urine, that is, water and the waste products of metabolism. In humans, the kidneys are two small organs situated near the vertebral column at the small of the back, the left lying somewhat higher than the
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). The nephrotic syndrome can result from a number of conditions including streptococcal infection in children leading to chronic glomerulonephritis, reaction to toxins, diabetes, collagen disease, and other end-stage kidney diseases. The major symptom is massive edema. Corticosteroid therapy has been successful in treating certain forms of the disease.

Nephrosis

 

an obsolete term for the nephrotic syndrome. The term was used to designate degenerative changes in the renal tubules accompanied by a massive excretion of protein in the urine, by a decrease in the protein content and an increase in the fat content of the blood, by edema, and by other symptoms.

Lipoid and amyloid nephroses were once classified as distinct diseases. Detailed histological studies of the kidneys, especially those studies that used the electron microscope and other research methods, have established that the glomeruli are affected in nephrosis as well as the tubules. Thus, there is no strict morphological difference between nephritis and nephrosis. Furthermore, clinical observations show that a disease that begins as lipoid nephrosis often acquires features of nephritis and, conversely, that glomerulonephritis develops into lipoid nephrosis.

nephrosis

[nə′frō·səs]
(pathology)
Degenerative or retrogressive renal lesions, distinct from inflammation (nephritis) or vascular involvement (nephrosclerosis), especially as applied to tubular lesions (tubular nephritis). Also known as nephrodystrophy; nephropathy.
References in periodicals archive ?
A hypercoaguable state may develop in minimal change disease for the following reasons: (a) increased platelet aggregation secondary to thrombocytosis and release of beta thromboglobulin for platelets; (b) increased procoagulant activity secondary to physical conditions of the nephrosis such as hemoconcentration and hyperviscosity; (c) increased production of factor V and factor VIII due to excessive urinary loss of protein S; (d) reduction of antithrombin III, which inhibits thrombin; and (e) hypertriglyceridemia can also lead to a hypercoaguable state.
Differential Diagnosis Acute Glomerulonephritis Nephrosis Gross hematuria Microhematuria may or may not be present Mild proteinuria Severe proteinuria Decreased GFR * Normal GFR * Hypertension Normal BP Mild edema Generalized edema Elevated BUN Normal BUN, creatinine Low C3 Normal C3 Normal cholesterol Elevated cholesterol * Glomerular filtration rate.
Michelle explained: "The doctors knew very little about the disease when we first went to them because Deborah was the first patient in Northern Ireland to be diagnosed with congenital nephrosis.
Today, the Japan Society of School Health performs mass screening for heart diseases such as congenital heart diseases, acquired heart diseases, and arrhythmias, respiratory diseases such as tuberculosis and asthma, and renal diseases such as hephritis and nephrosis.
Immune Globulin Intravenous (Human) (IGIV) products have been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, and death.
25] In this article stroke is used interchangeably with cerebrovascular disease, renal disease with nephritis and nephrosis, and cancers with malignant neoplasms.
moderate 1 - 1 hydronephrosis with cystitis Bilateral hydro nephrosis with thickened 1 1 bladder wall with cystitis Gross ascites with punctate discrete spots - 1 1 in lung parenchyma seen LT sided minimal pleural effusion with free - 1 1 fluid in abdominal cavity Massive hydronephrosis (It side) 1 - 1 Mild hepatomegaly 1 2 3 RT sided hydronephrosis with PUJ obstruction 1 1 Total 8 10 18 Chart 1: Pie graph showing sex distribution of total number of patients Male 57% Female 43% Note: Table made from pie chart.
1 K80-82 disease Nephritis and 580-589 N0-7, 17-19, nephrosis 25-27 Benign prostatic 600 N40 hyperplasia Maternal death 630-676 O00-99 Source: Nolte and McKee (24) Table 2.
Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis.
In other words, it the kid had had major nephrosis, his obstructed kidney would have atrophied, died, and been surgically removed.
Ochratoxicosis in young White Leghorn cockerels leads to acute nephrosis, hepatic degeneration and suppression of hematopoiesis.
Pigmentary nephrosis with moderate tubular degeneration and focal interstitial petechial hemorrhages were seen in the kidneys.