nephrosis


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Related to nephrosis: hydronephrosis

nephrosis

(nəfrō`səs), kidney disease characterized by lesions of the epithelial lining of the renal tubules, resulting in marked disturbance in the filtration function and the consequent appearance of large amounts of protein (albumin) in the urine (see urinary systemurinary system,
group of organs of the body concerned with excretion of urine, that is, water and the waste products of metabolism. In humans, the kidneys are two small organs situated near the vertebral column at the small of the back, the left lying somewhat higher than the
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). The nephrotic syndrome can result from a number of conditions including streptococcal infection in children leading to chronic glomerulonephritis, reaction to toxins, diabetes, collagen disease, and other end-stage kidney diseases. The major symptom is massive edema. Corticosteroid therapy has been successful in treating certain forms of the disease.

Nephrosis

 

an obsolete term for the nephrotic syndrome. The term was used to designate degenerative changes in the renal tubules accompanied by a massive excretion of protein in the urine, by a decrease in the protein content and an increase in the fat content of the blood, by edema, and by other symptoms.

Lipoid and amyloid nephroses were once classified as distinct diseases. Detailed histological studies of the kidneys, especially those studies that used the electron microscope and other research methods, have established that the glomeruli are affected in nephrosis as well as the tubules. Thus, there is no strict morphological difference between nephritis and nephrosis. Furthermore, clinical observations show that a disease that begins as lipoid nephrosis often acquires features of nephritis and, conversely, that glomerulonephritis develops into lipoid nephrosis.

nephrosis

[nə′frō·səs]
(pathology)
Degenerative or retrogressive renal lesions, distinct from inflammation (nephritis) or vascular involvement (nephrosclerosis), especially as applied to tubular lesions (tubular nephritis). Also known as nephrodystrophy; nephropathy.
References in periodicals archive ?
Effects of Chinese herbal medicine Huaiqihuang Granule on nephrin and podocin expressions in renal tissues of rats with adriamycin-induced nephrosis. Chin J Integr Med.
Soleiman et al., "Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis," American Journal of Pathology, vol.
This study also noted increased mortality from nephritis, nephrosis, heart failure, and brain infarction among both men and women with severely impaired tubular function.
The decrease of their content in the blood occurs in pancreatitis hypothyreosis, nephrosis, liver disease, hemolytic anemia and leukemia [8].
In nephrosis, the levels of serum AMG may increase as much as 10 times because of its large size aids in its retention.
Michael Kaback of the University of California at San Diego said Cajuns (Louisiana French-speakers) have higher rates than others for Tay-Sachs disease, while African-Americans suffer more from sickle-cell anemia, Vietnamese from thalassemia, Finns from congenital nephrosis and Northern Europeans from cystic fibrosis.
Renal function also is influenced by other factors, such as vascular disease, surgery, diabetes, age over 75, dehydration, heart failure, cirrhosis, or nephrosis. In addition, undergoing two contrast assays within 72 hours predisposes an individual to CIN.
For instance, students invited peers to: 1) compare the lung sounds of Client A (pneumonia), Client B (COPD), and Client C (atelectasis with chest tubes); 2) inspect and palpate the feet of two patients (one with arterial insufficiency, the other with venous problems); 3) examine and manipulate a new wound drainage system; 4) contrast the diagnostic lab data of a client undergoing alcohol detoxification with a person who exhibited Lithium toxicity on admission; or 5) assess two pediatric patients--one with nephrosis, the other with nephritis--including pertinent differences in vital signs, blood work, and urinalysis.
Mortality studies from cadmium-polluted areas in Europe and Japan have demonstrated that mortality rates for nephritis and nephrosis are higher than in control areas, although no increase in the incidence of cardiovascular deaths has been reported (27).
He studied lysosomes and peroxisomes in diverse cell types and tissues and in pathological conditions (such as fatty liver, tumors or nephrosis).