nerve growth factor


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nerve growth factor

[′nərv ‚grōth ‚fak·tər]
(neuroscience)
A multimeric protein that promotes nerve cell growth and may protect some types of nerve cells from damage, including nerve cells in the cholinergic system.
References in periodicals archive ?
The clinical research of rat nerve growth factor in the treatment of moderate to severe neonatal anaerobic ischemic encephalopathy.
Stimulation of nerve growth factor production by pyrroloquinoline quinone and its derivatives in vitro and in vivo.
Aiba, T., Mori, J., Nakai, Y., 1993, Nerve growth factor (NGF) and its receptor in rat olfactory epithelium.
With chlorpyrifos addition during mid-differentiation (four days after nerve growth factor pretreatment), ChAT was unaffected, but TH was increased slightly.
Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons.
Several years ago some very good neurologists--mainly from Albert Einstein College of Medicine in New York--conducted a protein therapy trial for diabetic neuropathy, using nerve growth factor, a completely different concept.
Louis's Washington University 50 years ago, Levi-Montalcini discovered nerve growth factor, one of the twentieth century's major neurobiological breakthroughs.
Neotrofin is a small molecule that crosses the blood-brain barrier, enhances memory and causes the production of neurotrophic factors including nerve growth factor, which are believed to lead to nerve regeneration and sprouting.
In a separate step, they produced microparticles from lactide-co-glycolide, in which nerve growth factor (NGF) and agents to alter its release were encapsulated.
Scientist Jon Cooper, from King's College, London, said: "Our findings suggest that nerve growth factor deprivation is responsible for the age related cell loss associated with Alzheimer's disease.