neural cell adhesion molecule


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neural cell adhesion molecule

[¦nu̇r·əl ‚sel ad′hē·zhen ‚mäl·ə‚kyül]
(neuroscience)
A calcium-independent cell adhesion molecule expressed by migrating neurons that mediates intercellular binding via homophilic mechanisms (by binding to other neural cell adhesion molecules); important in neuronal aggregation.
References in periodicals archive ?
Neural cell adhesion molecule expression in human pituitary adenomas.
The cell adhesion molecules N-cadherin and neural cell adhesion molecule regulate human growth hormone: a novel mechanism for regulating pituitary hormone secretion.
Polysialylated neural cell adhesion molecules expressed in human pituitary tumors and related to extrasellar invasion.
White et al., "Chemical characterization of a neural cell adhesion molecule purified from embryonic brain membranes," The Journal of Biological Chemistry, vol.
Dityatev, "In vivo synaptic plasticity in the dentate gyrus of mice deficient in the neural cell adhesion molecule NCAM or its polysialic acid," The European Journal of Neuroscience, vol.
Lee et al., "Conditional ablation of the neural cell adhesion molecule reduces precision of spatial learning, long-term potentiation, and depression in the CA1 subfield of mouse hippocampus," The Journal of Neuroscience, vol.
Abbreviations: BAX, BCL2-Associated X Protein; CDK, Cyclin Dependent Kinase; CK1, CDK Inhibitors; CSC, Cancer Stem Cell; EMT, Epithelial-Mesenchymal Transmission; ERK, Extracellular Signal-Regulated Kinases; FACS, Fluorescence-Activated Cell Sorting; MAP2, Microtubule-Associated Protein 2; MAPK, Mitogen-Activated Protein Kinases; MCL, Markov Cluster Algorithm; MMP, Matrix Metalloproteinase; MTT, 3-(4,5-Dimethylthiazol-2-YI)-2,5-Diphenyltetrazolium; NB, Neuroblastoma; NCAM, Neural Cell Adhesion Molecule; P13K, Phosphoinositide 3-Kinase; PSA, Polysialic Acid; SOX2, (Sex Determining Region Y)-Box 2; TGF, Transforming Growth Factor.
[4] Human genes: RUNX1, runt-related transcription factor 1; GATA1, GATA binding protein 1; SPI1, spleen focus forming virus proviral integration oncogene 1; NCAM1, neural cell adhesion molecule 1.
Amphibian-specific regulation of polysialic acid and the neural cell adhesion molecule in development and regeneration of the retinotectal system of the salamander Pleurodeles waltl.
Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule. Proc.
The other topics are polyunsaturated fatty acid deficiency, the correlation between vascular endothelial growth factor and proto-oncogene c-fos and c-myc, and the expression of neural cell adhesion molecules and osteonectin.