neural cell adhesion molecule


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neural cell adhesion molecule

[¦nu̇r·əl ‚sel ad′hē·zhen ‚mäl·ə‚kyül]
(neuroscience)
A calcium-independent cell adhesion molecule expressed by migrating neurons that mediates intercellular binding via homophilic mechanisms (by binding to other neural cell adhesion molecules); important in neuronal aggregation.
References in periodicals archive ?
Key words: Rana catesbeiana, optic tectum, cerebellum, neural cell adhesion molecule (NCAM), human natural killer cell antigen- 1 (HNK- 1), monoclonal antibodies
It has been proposed for salivary gland neoplasms that the propensity for perineural involvement is related to the expression of neural cell adhesion molecules by the neoplastic tumor cells.
Research objectives and content The Drosophila irregular chiasm C - roughest (irreC-rst) gene encodes a member of the DM-GRASP subgroup of the neural cell adhesion molecules of the immunoglobulin superfamily.
Neural cell adhesion molecules are important both for their role they play in the genesis and maintenance of synaptic connections, and therefore the understanding of neurological disorders and psychiatric conditions, and for their postulated role in the evolution of the human brain.