Neural Crest


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Neural crest

A strip of ectodermal material in the early vertebrate embryo inserted between the prospective neural plate and epidermis. After closure of the neural tube the crest cells migrate into the body and give rise to parts of the neural system: the main part of the visceral cranium, the mesenchyme, the chromaffin cells, and pigment cells. The true nature of the neural crest eluded recognition for many years because this primary organ has a temporary existence; its cells and derivatives are difficult to analyze when dispersed throughout the body. The fact that mesenchyme arises from this ectodermal organ was directly contrary to the doctrine of the specificity of the germ layers.

Neural crest no doubt exists, with similar qualities, in all vertebrate groups, including the cyclostomes. It has been most thoroughly studied in amphibians and the chick. See Germ layers

Neural Crest

 

the fold of ectoderm that borders the neural, or medullary, plate during neurulation in chordates and man. The cells of the neural crest become distributed over the neural tube after neurulation, forming the ganglionic primordia. The neural crest gives rise to the spinal and sympathetic ganglia, the visceral skeleton, the pigment cells, and the connective tissue layer of the skin.

neural crest

[′nu̇r·əl ′krest]
(embryology)
Ectoderm composing the primordium of the cranial, spinal, and autonomic ganglia and adrenal medulla, located on either side of the neural tube.
References in periodicals archive ?
The researchers traced the trajectories of primitive cells from mouse neural crest tissue -- a collection of cells that arise from the ectoderm, one of the primary germ-cell layers formed during embryonic development.
Factors controlling cardiac neural crest cell migration.
The sympathoadrenal lineage is derived from neural crest cells that aggregate on the dorsal aorta after migration through the ventral pathway [25].
The probable mechanism for the reduced number of ERC's is through inhibition of the expression of fibroblast growth factors in neural crest cells.
The origination of neuroblastic tumors from neural crest elements often enables them to express the enzymes required to produce catecholamines.
Embryology of the neural crest: its inductive role in the neurocutaneous syndromes.
Neural crest cells are developmentally flexible cells in embryos that help form the bones and cartilage of the face, some nerves and brain cells, smooth muscle and other tissues.
Con el objetivo de obtener informacion actual acerca de las similitudes moleculares entre los procesos de migracion de las CCN y la metastasis, asi como de las moleculas y las vias de senalizacion que son comunes tanto en las celulas cancerosas como en aquellas provenientes de la cresta neural, se buscaron en las bases de datos PubMed-Medline y Scholar Google, los terminos MeSH neural crest cells, tumor progression, cancer y metastasis, cruzando el termino neural crest cells con los demas por medio del operador booleano AND.
Se realizo una busqueda en PubMed a traves del descriptor en salud "neural crest" combinado con las expresiones "neurulation, evolution, embryonic and fetal development, craniofacialdevelopment" a traves de los conectores boleanos "AND" y "+".
It is classified under the category neurocristopathies--conditions originating from abnormal development of neural crest cells.
Professor Maya Sieber-Blum, from the university's Institute of Genetic Medicine, said: "We observed that the bulge, a region within hair follicles, contains skin stem cells that are intermixed with cells derived from the neural crest - a tissue known to give rise to Schwann cells.