Muller, "The two sites of fusion of the neural folds and the two neuropores in the human embryo," Teratology, vol.
Sadler, "Distribution of surface coat material on fusing neural folds of mouse embryos during neurulation," Anatomical Record, vol.
(a) Neuroepithelium thickens and converges; (b) formation of bilateral neural folds which are elevated (Mode 1); (c) apposing tips of neural folds aided by bending at the dorsolateral hinge points (DLHP) of the bilateral neural folds (Mode 2); (d) adhesion and fusion at the tips of the neural folds; (e) remodeling of the neural tube.
Convergent extension leads to narrowing and lengthening of the neuroepithelium, a process that has been suggested also to assist neural fold elevation via axial elongation [105, 226-228].
The second site of neural fold bending as described in Section 8.2 and Figure 3(c) is the dorsolateral hinge point (DLHP).
Copp, "EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion," The International Journal of Developmental Biology, vol.