neural tube defects


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neural tube defects

[‚nür·əl ′tüb ‚dē‚feks]
(medicine)
Congenital defects resulting from the incomplete closure of the neural tube during embryogenesis.
References in periodicals archive ?
One of the early studies showing the promise of folic acid beyond neural tube defects was published in 1996.
Some multi-vitamins may contain 400 micrograms of folic acid but many only contain 200 mcg, which is not enough to reduce the risk of neural tube defects.
Since folic acid fortification went into effect in 1998, the percentage of babies born with NTDs declined by 35 percent, according to the CDC analysis in the paper "Updated Neural Tube Defect Prevalence Estimates after Mandatory Folic Acid Fortification C United States, 1995-2011," published in today's MMWR.
are born with neural tube defects such as spina bifida, which is caused by the incomplete closing of the spine and skull.
In contrast to neural tube defects, however, the likelihood of a congenital heart defect increased steadily with increasing exposure.
Neural tube defects and folic acid-a South African perspective.
Neural tube defects are severe abnormalities of the central nervous system that develop in babies during the first few weeks of pregnancy resulting in malformations of the spine, skull, and brain, which may lead to seizures, intellectual disability, or sight problems, paralysis and a variety of urological and neurological complications.
Neural tube defects (NTDs) still affect 1 in 1000 pregnancies in the UK.
Previous figures have suggested one in 80 babies suffers a defect, which include Down's syndrome, congenital heart disease and neural tube defects such as spina bifida.
Previous figures suggested one in 80 babies suffered a defect, including Down's syndrome, congenital heart disease and neural tube defects such as spina bifida.
The timing of folic acid supplement usage is critical to preventing neural tube defects during pregnancy because the neural tube in the embryo closes by day 28 post-conception.
It is generally accepted among biochemists and those in the medical professions that, because of its function in the transferring of methyl groups (along with vitamin B-12), folic acid is involved in nucleic acid synthesis and thus aids in the prevention of neural tube defects in growing fetuses.