Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to neuralgia: trigeminal neuralgia


neuralgia (no͝orălˈjə, nyo͝o–), acute paroxysmal pain along a peripheral sensory nerve. Unlike neuritis, there is no inflammation or degeneration of nerve tissue. Neuralgia occurs commonly in the area of the facial, or trigeminal, nerve and brings attacks of excruciating pain at varying intervals. Often no cause can be found for trigeminal neuralgia, and in severe cases deadening of the nerve with novocaine or alcohol, or even surgical interruption of the nerve, is necessary to bring relief. Neuralgia can be caused by such disturbances as diabetes, infections, diseases of the nervous system, anemia, and extreme cold. The pain may occur for many months after an attack of shingles (see herpes zoster), and it is one of the symptoms of syphilitic involvement of the central nervous system. In many cases, pain can be relieved by hot applications, drugs, and various kinds of physiotherapy.
The Columbia Electronic Encyclopedia™ Copyright © 2022, Columbia University Press. Licensed from Columbia University Press. All rights reserved.
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



a pathological condition that is characterized by attacks of pain at the innervation site of a peripheral nerve. In contrast to neuritis, neuralgia does not involve motor disturbances or a loss of sensitivity, and structural changes in the affected nerve are not observed.

Neuralgias develop predominantly in nerves that pass through narrow canals and openings. With primary, or essential, neuralgia no accompanying diseases are clinically observed; with secondary, or symptomatic, neuralgia inflammatory processes, tumors, or other conditions harmful to nerves can arise. Should the neuralgia be prolonged, a neuritic stage can arise in which structural changes accompanied by a loss of sensitivity in the nerve become apparent.

Neuralgia produces paroxysmal pains and such autonomic vascular disturbances as reddening of the skin and lacrimation; sometimes localized muscle spasms in the form of painful tics occur. Neuralgia most commonly affects the trigeminal nerve; other nerves, such as the greater and lesser occipitals and the glossopharyngeal, are less frequently involved.

Secondary neuralgias are treated by curing the causative disease. In primary neuralgia, treatment involves injections of Novocain, topical use of Xylocaine, physiotherapy, and the use of B vitamins. Antispasmodics are specifically used for neuralgia of the trigeminal nerve.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


Pain in or along the course of one or more nerves. Also known as neurodynia.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.


severe spasmodic pain caused by damage to or malfunctioning of a nerve and often following the course of the nerve
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
The secondary aim was to identify any correlation between recurrence of pain and number of divisions of trigeminal nerve having neuralgia and also the recurrence of pain and age of the patient.
The primary imaging modality for evaluation of patients with trigeminal neuralgia is MRI (13).
The nerve comes out of the greater sciatic foramen, and passes through the ischial spine, sacrospinous ligament, and sacrotuberous ligament.[6,7] Pudendal neuralgia develops after mechanical damage to the pudendal nerve, viral infections, and immunological processes.[8] The mechanical damage to the nerve can be also called as pudendal nerve entrapment.
Trigeminal neuralgia is a neuropathic painful disorder that is brief in duration, electric shock-like in character, abrupt in onset and termination, and is restricted to the distribution of one or more division's of trigeminal nerve1.
Prof Khalid explained to the surgeons attending the three-day moot that extreme pain and muscle spasms in the face or trigeminal neuralgia, if not treated, could have a profound effect on the quality of life of a person.
Here, we present an unusual case of GP neuralgia where underlying cause was a giant tonsillolith and tonsillectomy on that side relieved the patient of his complaints.
This research objective was to assess the therapeutic efficacy and safety of BTX-A in treating patients of advanced age (>80 years old) with idiopathic trigeminal neuralgia (ITN).
Trigeminal Neuralgia also known as 'The Suicide Disease' is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
Classic trigeminal neuralgia (TN) is an episodic stabbing facial pain syndrome followed by a period of relief in the sensory distribution of the trigeminal nerve (cranial nerve V; CN V).
According to the diagnostic criteria of the International Classification of Headache Disorders, [3.sup.rd] edition (beta version), nervus intermedius (facial nerve) neuralgia (NIN) is a rare disorder characterized by brief paroxysms of pain felt deep in the auditory canal that sometimes radiates to the parieto-occipital region (3).
The company has reported top-line results from the Neucourse phase three clinical trial in patients with post-herpetic neuralgia and Alday phase three clinical trials in patients with fibromyalgia.