neuraminidase


Also found in: Dictionary, Thesaurus, Medical, Financial, Wikipedia.
Related to neuraminidase: sialic acid, Neuraminidase inhibitor

neuraminidase

[‚nu̇r·ə′min·ə‚dās]
(microbiology)
A bacterial enzyme that acts to split salic acid from neuraminic acid glycosides.
References in periodicals archive ?
In fact, published studies by others have recently reported IAP deficiencies and high neuraminidase levels in IBD patients.
Standardizing the influenza neuraminidase inhibition assay among United States public health laboratories conducting virological surveillance.
aureus strains have neuraminidase activity (2), and sepsis is associated with decreased sialylation of circulating transferrin (3).
The best of these inhibited neuraminidase derived from resistant flu strains at concentrations of only a few nanomoles per litre; current flu drugs required concentrations 10 to 100 times higher to do the same.
The new class of drugs sabotages neuraminidase and stops it functioning.
Thus, both neuraminidase and [beta]-galactosidase enzymes are inactive.
Evidence that treatment with a neuraminidase inhibitor offers significant benefit in people with influenza is growing," commented Dr.
Of the 24 AIVs, 16 subtypes were detected, representing nine hemagglutinin and seven neuraminidase subtypes.
Importantly, it has no cross-resistance with the neuraminidase inhibitors or adamantanes.
Combo therapy with neuraminidase inhibitors, ribavirin, adamantanes, and interferon was widely used for avian influenza A(H5N1), but due to the lack of controls it's hard to draw any conclusions as to whether this resulted in enhanced efficacy.
Andrew McCammon made a computer movie of slight structural shifts that can occur in the neuraminidase 1 enzyme (the N1 in H1N1), a protein found in avian and swine influenza viruses.
During the flu season each year, combating the different strains of the influenza virus becomes a public health priority, with treatment dependent upon two groups of antiviral drugs: neuraminidase inhibitors and M2 ion channel inhibitors.