neuritic plaque


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neuritic plaque

[nu̇‚rid·ik ′plak]
(pathology)
Abnormal clumps of degenerating neurons surrounding a core of amyloid protein; a characteristic pathological feature found in the brains of Alzheimer's disease patients.
References in periodicals archive ?
4 ] Amyvid is a radioactive diagnostic agent for Positron Emission Tomography (PET) imaging of the brain to estimate beta-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) and other causes of cognitive decline.
Food and Drug Administration (FDA) approved VIZAMYL for PET imaging of the brain to estimate beta amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for AD or other causes of cognitive decline.
18) Additionally, PiB binds to both diffuse and neuritic plaques, which may affect the in vivo signal.
Important Safety Information NeuraCeq(TM) can be used for the imaging of beta-amyloid neuritic plaque density in the brain.
8] Neurofibrillary tangles and neuritic plaques, the hallmarks of AD, can also be found in other neurodegenerative disorders, as well as in cognitively intact elderly.
As early as the 1920s, the neuropathological characteristics -- particularly nerve cell loss and the appearance of abnormal cell lesions called neurofibrillary tangles and neuritic plaques -- were observed in the brains of Down's individuals over 35 years of age.
Indication Neuraceq(TM) is indicated for Positron Emission Tomography (PET) imaging of the brain to estimate beta-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's disease (AD) and other causes of cognitive decline.
Vizamyl is indicated for PET imaging of the brain to estimate beta amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer s disease or other causes of cognitive decline.
Our observation of an elevated e4 frequency in the [pure Lewy body] and [Parkinson's dementia] groups in which the overall brain neuritic plaque burden is low suggests the possibility that ApoE isoforms also might modulate neurodegeneration by nonamyloidogenic mechanisms," they said.
However, our observation of an elevated e4 frequency in the [pure Lewy body] and [Parkinson's dementia] groups in which the overall brain neuritic plaque burden is low suggests the possibility that ApoE isoforms also might modulate neurodegeneration by nonamyloidogenic mechanisms, they pointed out.
The presence of beta-amyloid neuritic plaque in the brain may provide additional information to supplement a physician's clinical assessment of a patient with cognitive impairment.
Food and Drug Administration (FDA) approval of Vizamyl (Flutemetamol F18 injection), a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the brain to estimate beta amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer s disease (AD) or other causes of cognitive decline.