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(no͝orī`tĭs, nyo͝o–), inflammation of a peripheral nerve, often accompanied by degenerative changes in nervous tissue. The cause can be mechanical (injury, pressure), vascular (occlusion of a vessel or hemorrhage into nerve tissue), infectious (invasion by microorganisms), toxic (metallic or chemical poisoning, alcoholism), or metabolic (vitamin deficiencies, pernicious anemia). Symptoms of neuritis that arise from involvement of sensory nerves are tingling, burning, pin-and-needle sensations, or even loss of sensation. If motor nerves are involved, symptoms may range from a slight loss of muscle tone to paralysis. Since neuritis is regarded as a condition that results from a number of disorders, rather than a disease in itself, treatment is directed first at the underlying cause. See neuralgianeuralgia
, acute paroxysmal pain along a peripheral sensory nerve. Unlike neuritis, there is no inflammation or degeneration of nerve tissue. Neuralgia occurs commonly in the area of the facial, or trigeminal, nerve and brings attacks of excruciating pain at varying intervals.
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The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an inflammatory disease of the peripheral nerves. The symptoms of neuritis include pain, paralysis, pareses, and the decrease or loss of nerve sensitivity. Neuritides can result from a wide variety of causes. For example, otitis in the middle ear, and such infectious agents as the virus of herpes zoster can be involved in the pathogenesis of neuritis of the facial nerve. Catarrhal factors and traumas can also play a part in the development of this type of neuritis.

Polyneuritis is a special form of neuritis in which many nerves are involved in the disease process. Some polyneuritides are caused by a neurotropic virus. The roots of the spinal nerve are usually affected (as in polyradiculoneuritis), and often the spinal column and even the brain are affected. The most common causes of polyneuritides are chronic exogenous intoxications, such as those caused by alcohol, botulism toxin, and lead, or endogenous, intoxications, for instance, those resulting from diabetes and uremia.

Patients with neuritis experience pain in the extremities, muscular weakness, disturbances of sensitivity, atrophies and pareses of muscles, changes in skin coloring, sweating, and chilliness. These changes appear predominantly in the regions of the hands and feet. Neuritis is treated by first curing the causative disease and then using antibiotics, analgesics, sedatives, and B vitamins. Physiotherapy is also indicated.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.


Degenerative or inflammatory nerve lesions associated with pain, hypersensitivity, anesthesia or paresthesia, paralysis, muscular atrophy, and loss of reflexes in the innervated part of the body.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.


inflammation of a nerve or nerves, often accompanied by pain and loss of function in the affected part
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
All patients had previously been treated with high doses of intravenous methylprednisolone (IVMP) for exacerbations of optic neuritis. All of the patients were treated with an initial IVIg dose of 0.4 gr/kg/day for 5 consecutive days, and then 0.4 gr/kg for each month.
Optic neuritis (acute and chronic) without multiple sclerosis was detected too in 6.89% of the total patients.
Neuro myelitis optica spectrum disorders (NMOSD) and NSS associated optic neuritis and myelitis clearly share many features in common.
Dr Adatia said: "In 15-20 per cent of cases, those who eventually develop Multiple Sclerosis [MS], optic neuritis is their first symptom.
Out of the total number of relapses, the cerebral sensory relapses were the highest compared to the cerebral motor, cerebellar, optic neuritis, or autonomic relapses.
Thinner slice and contrasted study should have been performed for the definite diagnosis of optic neuritis.
HZO is defined as the reactivation of VZV inside the ophthalmic branch of the trigeminal nerve [7], commonly manifesting as conjunctivitis, anterior uveitis, or keratitis and rarely presenting with optic neuritis [8].
The aim of our research was to find the association of IL-17A and CYP4F2 rs1558139 gene polymorphism with optic neuritis.
Sensory and optic neuritis are suggested the common clinical features of paediatric multiple sclerosis in Pakistan.
This patent allowance will help secure the path forward for the continued clinical development of MP101 in Huntington's Disease, optic neuritis and Duchenne's muscular dystrophy.
Kancera's pharmaceutical candidate KAND567 works by blocking the Fractalkine system and has been shown in preclinical disease models to effectively counteract the onset of autoimmune disorders, as well as neuritis and pain in connection with chemotherapy against cancer.