(redirected from neurofibromas)
Also found in: Dictionary, Thesaurus, Medical.


A tumor characterized by the diffuse proliferation of peripheral nerve elements. Also known as endoneural fibroma; myxofibroma of nerve sheath; neurofibromyxoma; perineural fibroblastoma; perineural fibroma.



a benign tumor that originates in membranes of peripheral nerves and is localized in any part of the body along the path of a nerve trunk. Neurofibromas most often affect the sciatic and intercostal nerves. The multiple occurrence of neurofibromas is called neurofibromatosis.

References in periodicals archive ?
Histopathologic examination identified the mass as a neurofibroma.
Neurofibromas have previously been reported in an adult green-winged macaw (Ara chloroptera).
Complete surgical excision remains the gold-standard treatment for neurofibromas.
Forty-nine consecutive specimens of partially neurotized melanocytic nevi (43 patients) and 49 consecutive specimens of neurofibromas (43 patients) were selected from the surgical pathology archives at Washington University Medical Center (St Louis, Missouri) from 2006 through 2008.
9) Different therapeutic approaches are currently available to reduce the complications of the disease and surgery for removing a neurofibroma is often only advised if it can compress important structures, if it is thought to be malignant, or to correct any bone malformations.
Please rank the following manifestations of NF1 in order of importance to treat if a clinical trial were to open (1 is most important and 6 is least important): --Skin tumors --Plexiform neurofibromas --Malignant peripheral nerve sheath tumors --Optic gliomas --Cafe-au-lait macules --Learning disability 6.
Patients with NF1 have an increased risk of developing tumors of the central and peripheral nervous system including plexiform neurofibromas (27%), optic gliomas (15-20%), pheochromocytomas (1%), malignant peripheral nerve sheath tumors (5%), and neurofibrosarcomas (6%).
I HAVE lumps on my arms and legs that I'm told are neurofibromas.
Surgery to ensure that the tumor was benign confirmed neurofibromas on her facial nerve, which couldn't be removed without causing facial paralysis.
In May, 2012 the EMA designated AR-42 an orphan drug for the treatment of neurofibromatosis type 2 (NF2), a rare genetic disorder characterized by the growth of noncancerous tumors in the brain and spinal cord, juvenile cataracts and neurofibromas of the skin.
They are non-epithelial benign tumours of mesodermal orgin, a category that also includes leiomyomas, fibromas, neurofibromas and lymphangiomas.