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A tumor characterized by the diffuse proliferation of peripheral nerve elements. Also known as endoneural fibroma; myxofibroma of nerve sheath; neurofibromyxoma; perineural fibroblastoma; perineural fibroma.



a benign tumor that originates in membranes of peripheral nerves and is localized in any part of the body along the path of a nerve trunk. Neurofibromas most often affect the sciatic and intercostal nerves. The multiple occurrence of neurofibromas is called neurofibromatosis.

References in periodicals archive ?
Melanocytic differentiation is present in a significant proportion of nonpigmented diffuse neurofibromas: a potential diagnostic pitfall.
Patients with NF 1 require PET scanning with FDG to differentiate between benign neurofibromas or schwannomas and malignant peripheral nerve sheath tumours (MPNSTs).
Differentiation between neurofibromas and malignant peripheral nerve sheath tumors in neurofibromatosis 1 evaluated by MRI.
Los neurofibromas cutaneos estan presentes en un 30% de los enfermos y, generalmente se manifiestan en la adolescencia, y continuan apareciendo y desarrollandose a lo largo de la edad adulta (1).
CLSM appears to be a simple and low-cost technique to differentiate morphological features of apparently identical populations of Schwann cells and, thus, to differentiate forms of neurofibromas with low and high risk of recurrence and malignant degeneration.
In contrast to cutaneous neurofibromas which grow intraneurally, PNFs can involve an entire plexus of nerves and demonstrate an infiltrative pattern.
Gastric neurofibromas at CT scan exhibit hypoattenuated mass lesion with usually well-defined borders.
The histologic features of diffuse neurofibroma involving the parotid region are similar to those seen in diffuse neurofibromas of the skin or other sites.
Imaging findings and MRI in particular are obligatory for head and neck region neurofibromas and central nervous system manifestations in NF1 patients and also during follow ups.
Caption: FIGURE 1: Neurofibromas and cafe au lait spots on the skin.