"With the stump there's still some of the plexiform neurofibroma
Melanocytic differentiation is present in a significant proportion of nonpigmented diffuse neurofibromas
: a potential diagnostic pitfall.
Patients with NF 1 require PET scanning with FDG to differentiate between benign neurofibromas
or schwannomas and malignant peripheral nerve sheath tumours (MPNSTs).
Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas
: a neurofibromatosis Clinical Trials Consortium phase II study.
Differentiation between neurofibromas
and malignant peripheral nerve sheath tumors in neurofibromatosis 1 evaluated by MRI.
cutaneos estan presentes en un 30% de los enfermos y, generalmente se manifiestan en la adolescencia, y continuan apareciendo y desarrollandose a lo largo de la edad adulta (1).
CLSM appears to be a simple and low-cost technique to differentiate morphological features of apparently identical populations of Schwann cells and, thus, to differentiate forms of neurofibromas
with low and high risk of recurrence and malignant degeneration.
In contrast to cutaneous neurofibromas
which grow intraneurally, PNFs can involve an entire plexus of nerves and demonstrate an infiltrative pattern.
at CT scan exhibit hypoattenuated mass lesion with usually well-defined borders.
The histologic features of diffuse neurofibroma
involving the parotid region are similar to those seen in diffuse neurofibromas
of the skin or other sites.
Imaging findings and MRI in particular are obligatory for head and neck region neurofibromas
and central nervous system manifestations in NF1 patients and also during follow ups.
Caption: FIGURE 1: Neurofibromas
and cafe au lait spots on the skin.