neurofibrosarcoma


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neurofibrosarcoma

[¦nu̇r·ō‚fī·brō·sär′kō·mə]
(medicine)
A malignant tumor composed of interlacing bundles of anaplastic spindle-shaped cells which resemble those of nerve sheaths.
References in periodicals archive ?
Multicentric neurofibrosarcoma in a Canada goose, Branta canadensis.
8,9) Peripheral nervous system neoplasias include neurofibromas, neurofibrosarcomas, and lymphosarcomas.
Malignant neurogenic lesions include malignant paragangliomas and neurofibrosarcomas.
Malignant schwannoma--also known as neurogenic sarcoma, neurofibrosarcoma, malignant neurofibroma, and recently renamed malignant peripheral nerve sheath tumor--is a rare form of cancer that accounts for 5% of all soft-tissue tumors and affects 0.
Malignant transformation to neurofibrosarcomas (Figs 18 a and b) and malignant schwannomas is extremely rare.
Patients with NF1 have an increased risk of developing tumors of the central and peripheral nervous system including plexiform neurofibromas (27%), optic gliomas (15-20%), pheochromocytomas (1%), malignant peripheral nerve sheath tumors (5%), and neurofibrosarcomas (6%).
While neurofibrosarcomas are a particularly aggressive form of cancer with a poor outcome, they are fortunately relatively uncommon and Nfl is not life-threatening for the majority of people who have the condition.
Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis.
9] Irradiation has been reported to cause neurofibromas to change into a neurofibrosarcomas in patients with neurofibromatosis.